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Male Breast Cancer Treatment

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Last Updated: 21 October 2020

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General | Latest Info

Although it is rare, men can get breast cancer. Learn about symptoms of breast cancer in men and things that may increase your risk. Breast Cancer is most often found in women, but men can get breast cancer too. About 1 out of every 100 breast cancers diagnosed in the United States is found in men. The most common kinds of breast cancer in men are the same kinds in women invasive ductal carcinoma. Cancer cells grow outside ducts into other parts of breast tissue. Invasive cancer cells can also spread, or metastasize, to other parts of the body. Invasive lobular carcinoma. Cancer cells spread from lobules to breast tissues that are close by. These invasive cancer cells can also spread to other parts of the body. Ductal carcinoma in situ is a breast disease that may lead to breast cancer. Cancer cells are only in the lining of ducts and have not spread to other tissues in the breast.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

Changes to This Summary (08/28/2020)

HER2-targeted therapies are used to treat HER2-positive breast cancers.

Drug nameBrand name(s)Pill, injection under the skin, or IV drug (given by vein through an IV)?
TrastuzumabHerceptin (IV drug), Herceptin Hylecta (injection)IV drug or injection
PertuzumabPerjetaIV drug
Pertuzumab, trastuzumab and hyaluronidase-zzxfPhesgoInjection
Ado-trastuzumab emtansine (T-DM1)KadcylaIV drug
Fam-trastuzumab deruxtecan (trastuzumab deruxtecan)EnhertuIV drug
TucatinibTukysaPill
NeratinibNerlynxPill
LapatinibTykerbPill

In the United States, approximately 276 480 new cases of female invasive Breast Cancer are predicted to occur in 2020, along with 2620 cases in men. Among US women in 2020, in addition to invasive Breast Cancer, 48 530 new cases of ductal carcinoma in situ are expected to be diagnose. The incidence of Breast Cancer in the United States increased rapidly from 1980 to 1987, largely as a consequence of widespread use of mammography screening, which led to increased detection of asymptomatic small breast tumors. After 1987, increase in overall rates of invasive breast cancers slowed significantly, specifically among white women aged 50 years or older. Incidence over this period of time varies dramatically by histologic type. Common ductal carcinomas increased modestly from 1987 to 1999, whereas invasive lobular and mixed ductal - lobular carcinomas increased dramatically during this time period. For women under the age of 50, Breast Cancer rates have remained stable since the mid to late 1980s. Rates of DCIS have stabilized since 2000. Whereas decline in invasive Breast Cancer rates was evident as early as 1999, rates decreased dramatically in women aged 50 years or older between 2001 and 2004. During this same period, no significant change was observed in the incidence of ER - negative cancers or cancers in women younger than 50 years. The decline in rates from 2001 to 2004 was greatest between 2002 and 2003 and was limited to non - Hispanic whites. The reason for the decline has been extensively debate. Breast Cancer rates decreased significantly after reports from Million Women Study and Womens Health Initiative showing higher numbers of breast cancers in women using combination HRT with estrogen and progestin for menopausal symptoms. A Near - immediate decrease in use of combination HRT for that purpose has been widely accepted as the primary explanation for the decrease in Breast Cancer rates. However, Jemal and Li argue that the decline in Breast Cancer incidence starts earlier than reduction in combination HRT use and that decline is due in part to saturation in mammographic screening mammography that produced plateau in incidence when such screening stabilized in late 1990s. Saturation of the population would be predicted to reduce the pool of undiagnosed or prevalent cases. For women aged 69 years or older, Breast Cancer rates started to decline as early as 1998, when screening first showed plateau. This observation is consistent with the prediction that if widespread screening and earlier detection are effective, they should result in peak incidence among women during the sixth and seventh decades of life, followed by decline. This is exactly the pattern now being reported for screened populations. The second observation noted by Jemal et al was that despite evidence for plateau effect, screening saturation alone could not explain dramatic declines or pattern of decline.


January 2020

01 / 22 / 2019 FDA finalizes policy on labeling for drugs approved under accelerated approval, reflecting more frequent use of this pathway for drugs use in certain clinical settings. 01 / 17 / 2019 FDA alerts health care professionals of possible increased risk of death associated with specific drug - containing balloons and stents in certain patients with peripheral arterial disease 01 / 17 / 2019 FDA take New steps to advance development of antimicrobial susceptibility test devices that help identify appropriate drug treatments for infections and reduce overuse of antibiotics 01 / 16 / 2019 New policy to encourage development of treatments for rare diseases 01 / 09 / 2019 E. Coli outbreak link to romaine lettuce grow in certain California counties end, FDAs investigation into source of contamination continue


November 2019

11 / 26 / 2019 FDA issues warning letter for products illegally marketed for treatment of health conditions, including opioid withdrawal symptoms 11 / 25 / 2019 FDA explains policy for manufacturers of battery - operate tobacco products and e - liquids who are considering making limited safety - related modifications to their products 11 / 22 / 2019 FDA warn consumers not to eat romaine lettuce grow in Salinas, California 11 / 19 / 2019 FDA issues draft guidance on compounding certain animal drugs from bulk drug substances 11 / 15 / 2019 FDA recommend discarding or destroying yellowfin / ahi tuna import from Truong Phu Xanh Co., Ltd with production dates in 2019 11 / 15 / 2019 FDA issues final guidance for development of smallpox treatments as part of critical preparedness efforts 11 / 14 / 2019 FDA expands work with Scholastic with launch of new youth e - cigarette prevention educational resources for middle and high schools 11 / 52019 FDA reminds patients, health care professionals and laboratory personnel about potential for biotin interference with certain test results, especially specific tests to aid in heart attack diagnose 11 / 42019 FDA provide updates on ongoing postmarket activities for Essure device 11 / 12019 FDA propose new rule to establish lab accreditation program to help improve reliability of some human and animal food testing


Treatment of Early/Localized/Operable Male Breast Cancer

In men, no control studies have compared adjuvant treatment options. Adjuvant therapies used to treat early / localized / Operable male Breast Cancer are outlined in Table 3. In men with node - negative tumors, adjuvant therapy should be considered on the same basis as for women with Breast Cancer because there is no evidence that response to therapy is different between men and women. In men with node - positive tumors, both chemotherapy plus tamoxifen and other hormonal therapy have been used and are believed to increase survival to the same extent as in women with Breast Cancer. Approximately 85% of all male breast cancers are estrogen receptor - positive, and 70% of them are progesterone receptor - positive. Response to hormone therapy correlates with the presence of these receptors. Hormonal Therapy has been recommended in all patients with receptor - positive cancers. Tamoxifen use, however, is associated with a high rate of Treatment - limiting symptoms, such as hot flashes and impotence, in male Breast Cancer patients. Responses are generally similar to those seen in women with Breast Cancer. Regarding endocrine therapy, tamoxifen is generally used instead of aromatase inhibitor because data supporting use of AI in men with Breast Cancer is limit. Retrospective analysis of 257 men with stage I to stage III Breast Cancer include 50 men treated with AI and 207 men treated with tamoxifen. The following results were observed: use of AI Therapy with luteinizing hormone - releasing hormone agonist has been reported in several cases in literature. German Breast Group is conducting a randomized phase II clinical trial of tamoxifen with or without gonadotropin - releasing hormone analogue versus AI plus GnRH analogue in men with Early - stage, hormone receptor - positive Breast Cancer; results are pending.

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Table

CDK4/6 InhibitorSide Effects
AbemaciclibSome possible side effects include diarrhea, low white blood cell counts, low red blood cell counts (anemia), blood clots, nausea, abdominal pain, fatigue and vomiting. In some cases, it can cause liver problems. Your liver function will be checked before treatment begins and throughout your treatment. In rare cases, it can cause lung inflammation, which can cause death. Tell your provider right away if you have shortness of breath or other breathing problems while taking this drug.
PalbociclibSome possible side effects include low white blood cell counts, low red blood cell counts (anemia), fatigue, nausea, mouth sores, hair thinning, diarrhea and in rare cases, blood clots. In rare cases, it can cause lung inflammation, which can cause death. Tell your provider right away if you have shortness of breath or other breathing problems while taking this drug.
RibociclibSome possible side effects include low white blood cell counts, nausea, fatigue, diarrhea, hair loss, vomiting, constipation, headache and back pain. In some cases, it can cause liver problems. Your liver function will be checked before treatment begins and throughout your treatment. In rare cases, it can cause changes on an EKG (electrocardiogram). An EKG gives information on the electrical activity of the heart. You will get an EKG before treatment begins and throughout your treatment to check for any changes. In rare cases, it can cause lung inflammation, which can cause death. Tell your provider right away if you have shortness of breath or other breathing problems while taking this drug.

Table2

Tyrosine-Kinase InhibitorsSide Effects
Tucatinib, neratinib or lapatinibThe most common side effect is diarrhea. Your health care provider will recommend medications to help control the diarrhea. Other possible side effects include nausea, vomiting and fatigue. In rare cases, each of these drugs has been linked to liver problems. Your liver function will be checked throughout your treatment.

Table3

PARP InhibitorSide Effects
OlaparibSome possible side effects include low red blood cell counts (anemia), nausea, vomiting, fatigue and low white blood cell counts. In rare cases, it can cause acute myeloid leukemia.
TalazoparibSome possible side effects include fatigue, low red blood cell counts (anemia), nausea, vomiting, headache and diarrhea. In rare cases, it can cause acute myeloid leukemia.

Table4

Which tumors are tested?What does the tumor test determine?How do the test results guide treatment?
All tumorsHormone receptor status (estrogen and progesterone receptor status)If the cancer is hormone receptor-positive , the first treatment is usually hormone therapy , often with a CDK4/6 inhibitor .
All tumorsHER2 statusIf the cancer is HER2-positive, HER2-targeted therapies , such as trastuzumab (Herceptin), are included in the treatment plan.
Tumors that are both hormone receptor-positive and HER2-negativeWhether the tumor has a PIK3CA gene mutationIf the tumor has a PIK3CA gene mutation, the cancer may be treated with the PI3 kinase inhibitor alpelisib and the hormone therapy fulvestrant.
Triple negative breast cancers (tumors that are both hormone receptor-negative and HER2-negative)PD-L1 statusIf the cancer is PD-L1-positive, the first treatment may be the immunotherapy drug atezolizumab (Tecentriq) in combination with chemotherapy .
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Diagnosis

Once your doctor has diagnosed you with breast cancer, he or she works to establish the extent of your cancer. Your cancer stage helps determine your prognosis and best treatment options. Tests and procedures used to stage Breast Cancer may include: bone scan, computerized tomography scan, Positron emission tomography scan. Breast Cancer stages range from 0 to IV with 0 indicating cancer that is noninvasive or contained within milk ducts. Stage IV Breast Cancer, also called metastatic Breast Cancer, indicates cancer that has spread to other areas of the body. Breast Cancer staging also takes into account your cancer's grade; presence of tumor markers, such as receptors for estrogen, progesterone and HER2; and proliferation factors.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

Clinical trials

Draft guidance, Male Breast Cancer: Developing Drugs for Treatment, includes draft recommendations for inclusion of males in Breast Cancer clinical trials. Historically, males either have not been included in clinical trials for Drugs to treat Breast Cancer or inclusion of males in those trials has been very limited; When finalize, draft guidance will provide clarity for industry regarding clinical development of Drugs to treat Breast Cancer in male patients. Fda, agency within the US Department of Health and Human Services, protects public health by assuring safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices. The agency is also responsible for the safety and security of our nation's food supply, cosmetics, dietary supplements, products that give off electronic radiation, and for regulating tobacco products.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

Coping and support

About 2 670 US men are estimated to have been diagnosed with Breast Cancer this year. Male Breast Cancer comprises less than 1% of all Breast Cancer cases. Give its rarity, there are lot of misconceptions and stigma surrounding Male Breast Cancer, which often results in a lot of stress and anxiety in men who have been diagnosed with the disease. Furthermore, lack of male - centric information regarding Breast Cancer can bring about psychological distress. Dealing with this condition can be very tough, not just physically, but also emotionally and spiritually. Thankfully, there are ways to deal with stress and other psychological effects that come with Male Breast Cancer diagnosis. Experiencing stress or anxiety is a natural part of life; however, in the context of Breast Cancer diagnosis, these feelings can become very overwhelming. Men with Breast Cancer experience anxiety and depressive symptoms, as well as traumatic stress symptoms. Men with Breast Cancer are also at risk of developing avoidant coping strategies and negative physical issues as well as feelings of fear and uncertainty when it comes to their diagnosis. While primary treatment options like mastectomy and chemotherapy focus on healing your physical body, alternative forms of treatment like psychotherapy can help you deal with the psychological effects of Male Breast Cancer. Therapy can strengthen your mind and equip you with positive coping mechanisms in order to overcome stress of your illness. Problem - solving therapy has been found to reduce psychological distress in adult cancer patients. Meanwhile, hypnotherapy can be used to manage psychological symptoms, as well as physical pain and other side effects of cancer treatment. You can also combine psychotherapy with mindfulness - base activities as a way of overcoming the stress of Male Breast Cancer. For example, meditation can be a wonderful way to access your thoughts and emotions regarding Breast Cancer, but in a non - judgmental and stress - free environment. The Mindfulness - base stress reduction program helps cancer patients by reducing physical and psychological symptoms such as stress, mood disturbances, fatigue and sleep disorders. Regular exercise is a common way for men to deal with their Breast Cancer diagnosis. Staying fit and active can relieve a lot of Cancer - related stress because a stronger body will be more capable of dealing with surgery, chemotherapy and other concerns related to Male Breast Cancer. It can also feel empowering to know that you are doing everything you can to recover and reduce the risk of Breast Cancer growing or recurring and can offer patients a sense of control when they are at their lowest point. Another way to stay fit is by adopting a healthier diet. Aim to incorporate more vegetables, fruits, lean chicken, fatty fish and whole grains into your diet. Apart from being nutritious, these ingredients are also known for reducing stress hormones in the body. Meanwhile, you should avoid unhealthy foods such as red meat and processed foods that are high in sugar and fat. Habits that fuel cancer, such as smoking and drinking alcohol, should also be avoid. Male Breast Cancer is a serious disease.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

What Are the Risk Factors?

Anything that increases the chance of a person developing cancer is a risk factor. Doctors have identified several risk factors for Male Breast Cancer. Brca mutations: Normal BRCA1 and BRCA2 genes suppress development of tumors. People with mutated BRCA gene have a higher risk of Breast Cancer. Between 8% - 15% of Male Breast Cancer patients have BRCA mutation, compared to 5% - 10% of female Breast Cancer patients. In addition to causing Breast Cancer, BRCA mutations are also linked to ovarian cancer, pancreatic cancer and melanoma. Family history of Breast Cancer: Risk of Breast Cancer is double for men who have parent, sibling or child with disease. Age: As men age, their chances of developing Breast Cancer increases. Obesity, Gynecomastia, or enlarged breasts caused by hormone imbalance or certain medications. Radiation exposure, often as part of Treatment for another Cancer Race: African - American Men have a higher risk of Male Breast Cancer than non - Hispanic white men.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

Surgery

An operation called mastectomy is the main type of surgery for Breast Cancer in men. It involves removing all breast tissue from affecting your breast as well as your nipple, and possibly also glands in your armpit and some muscle under your breast. The operation is done under general anaesthetic. You 'll probably need to stay in hospital for 1 to 2 days. It can take several months to fully recover. The Royal College of Surgeons of England has a leaflet for people recovering from mastectomy with detailed information and advice.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

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Hormone therapy

Hormone therapy drugs for metastatic breast cancer

DrugBrand nameUsed in pre- or postmenopausal women?Injection or pill?
AnastrozoleArimidexPostmenopausalPill
ExemestaneAromasinPostmenopausalPill
FulvestrantFaslodexPostmenopausalInjection
GoserelinZoladexPremenopausalInjection
LetrozoleFemaraPostmenopausalPill
LeuprolideLupronPremenopausalInjection
Megestrol acetateMegacePre- and postmenopausalPill
TamoxifenNolvadexPre- and postmenopausalPill
ToremifeneFarestonPostmenopausalPill

Hormone Therapy is a way to treat cancer by using hormones or drugs or other treatments that affect hormones. Hormone Therapy is a form of systemic therapy, like chemotherapy. It can be used after surgery to help lower the risk of cancer coming back, or before surgery. It is also used to treat cancer that has spread, or cancer that has come back after treatment. Some breast cancers grow in response to hormones, estrogen or progesterone. Estrogen and progesterone are usually thought of as female hormones, but men have them in their bodies also, just at lower levels. About 9 of 10 breast cancers in men are hormone receptor - positive. This makes them more likely to respond to hormone treatments. Breast cancers can be estrogen receptor - positive, or progesterone receptor - positive, or both. Hormone Therapy does not help people whose tumors are both ER - and PR - negative. Cardoso F, et al. Characterization of Male Breast Cancer: results of EORTC 10085 / TBCRC / BIG / NABCG International Male Breast Cancer Program. Annals of Oncology 0: 1 - 13 2017. Davies C, Pan H, Godwin J, et al. Long - term effects of continuing Adjuvant Tamoxifen for 10 years versus stopping at 5 years after diagnosis of oestrogen receptor - positive Breast Cancer: ATLAS, randomise Trial. Lancet. 2013; 381: 805 - 816. Erratum In: Lancet. 2013 Mar 9; 381: 804. Dimitrov NV, Colucci P, Nagpal S. Some aspects of Endocrine profile and management of hormone - dependent Male Breast Cancer. Oncologist. 2007; 12 - 798 - 807. Di Lauro L, Vici P, Del Medico P, Laudadio L, Tomao S, Giannarelli D, Pizzuti L, Sergi D, Barba M, Maugeri - Sacca M. Letrozole combine with gonadotropin - releasing hormone analog for metastatic Male Breast Cancer. Breast Cancer Res Treat. 2013 Aug; 141: 119 - 23. Epub 2013 Aug 28. Giordano SH. Review of diagnosis and management of Male Breast Cancer. Oncologist. 2005; 10: 471 - 479. Giordano SH, Perkins GH, Broglio K, Garcia SG, Middleton LP, Buzdar AU, Hortobagyi GN. Adjuvant systemic Therapy for Male Breast carcinoma. Cancer. 2005 Dec 1; 104: 2359 - 64. Gray RG, Rea D, Handley K, et al. Long - term effects of continuing Adjuvant Tamoxifen for 10 years versus stopping at 5 years in 6 953 women with early Breast Cancer. J Clin Oncol june 2013 vol. 31 no. 18_suppl 5. Jain S and Gradishar WJ. Chapter 61: Male Breast Cancer. In: Harris JR, Lippman ME, Morrow M, Osborne CK, eds. Diseases of Breast. 5 ed. Philadelphia, Pa: Lippincott - Williams & Wilkins; 2014. Losurdo et al. Controversies in clinicopathological characteristics and Treatment strategies of Male Breast Cancer: review of literature. Critical Reviews in Oncology / Hematology 113 283 - 291. Pdq Adult Treatment Editorial Board. Male Breast Cancer Treatment: Health Professional Version. 2017 Dec 15. In: PDQ Cancer Information Summaries. Bethesda: National Cancer Institute; 2002 -. Available from: https: / www - ncbi - nlm - nih - gov. Ezproxyhost. Library. Tmc. Edu / books / NBK65792 /. Access Jan 10 2018. Stearns V and Davidson NE. Chapter 45: Adjuvant Chemo Endocrine Therapy. In: Harris JR, Lippman ME, Morrow M, Osborne CK, eds. Diseases of Breast. 5 ed. Philadelphia: Wolters Kluwer Health; 2014. Zagouri F, Sergentanis TN, Chrysikos D, Zografos E, Rudas M, Steger G, Zografos G, Bartsch R. Fulvestrant and Male Breast Cancer: case series.

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Table

Premenopausal (before menopause) womenPostmenopausal (after menopause) womenMen
Tamoxifen Tamoxifen plus ovarian suppression Aromatase inhibitor plus ovarian suppressionTamoxifen Aromatase inhibitorTamoxifen

Table2

DrugBrand nameUsed in pre- or postmenopausal women?Injection or pill?
TamoxifenNolvadexPre- and postmenopausalPill
AnastrozoleArimidexPostmenopausalPill
LetrozoleFemaraPostmenopausalPill
ExemestaneAromasinPostmenopausalPill
GoserelinZoladexPremenopausalInjection
LeuprolideLupronPremenopausalInjection
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Lymph Nodes

Lymph nodes reveal information about the outlook and they help doctors determine the best types of treatment against cancer. Your lymph nodes act as filters for your body's lymphatic drainage system. That's why lymph nodes are likely to catch or filter out cancer cells that might be floating in fluid that drains away from cancerous area of the breast. Surgeons will inject blue dye and radioactive substance into the tumor or skin over the tumor. First, lymph nodes that turn blue and pick up tracers are called sentinel lymph nodes. Lymph nodes or nodes are then removed and sent to a pathologist, who looks to see if they contain any cancer cells. If no cancer cells are find, then no additional lymph node surgery is done. If cancer cells are found in nodes, then more underarm lymph nodes usually need to be remove. This is called axillary lymph node dissection. There are three levels of axillary lymph nodes: level I is the lowest level, closest to the breast. Level II is under main muscle that sweeps through the armpit. Level III refers to lymph nodes just above this muscle. Standard axillary lymph node dissection removes lymph nodes from levels I and II. If lymph nodes feel or look abnormal before surgery, then standard axillary lymph node removal is usually done. Your surgeon may still use dye, tracer, or both to make sure that all of important lymph nodes are identified and remove. Potential side effect of lymph node removal is lymphedema of the arm. This is a buildup of lymph fluid in soft tissues of the arm along with swelling. You can think of lymphedema as a plumbing problem: veins and lymphatic channels are like pipes and drains that can handle a normal load of lymphatic fluid. If lymph nodes and channels are remove, there might not be enough pipes and drains to handle all fluid and arm swells. Lymphedema can happen just weeks after lymph node surgery or years after initial cancer treatment. Factors that can bring on lymphedema include: traumas in muscles or skin of the arm that can lead to infection. These include scratches, bug bites, sunburn, kitchen burns, garden cuts, plant rashes, skin cracking from chronic dryness, and skin tears from nervous picking habits. Gaining a lot of weight after Breast Cancer treatment. Like being overweight to start with, gaining weight increases your risk for arm swelling. Heat. Heat widens blood vessels and increases circulation to the arm. As a result, extra fluid can seep into tissues of the arm. Drainage pipes of arm may not be able to handle extra fluid load, leading to swelling. Very hot weather and sitting in hot tubs can bring on lymphedema. Blood clots. Occasionally, blood clot in the axillary vein will back up fluid in the arm.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

Inflammatory breast cancer

Inflammatory Breast Cancer is a rare type of breast cancer that often starts in soft tissues of the breast and causes lymph vessels in the skin of the breast to become blocked. As a result, breast may become firm, tender, itchy, red and warm due to increased blood flow and build - up of white blood cells. This type of cancer is distinct from other types, with major differences in symptoms, prognosis and treatment. The term inflammatory refers only to the appearance of breasts. When breasts become inflamed due to infection or injury, they often become tender, swell, red and itchy. However, underlying cause of IBC is unrelated to inflammation. Because of similarities in symptoms, IBC may at first be diagnosed as breast infection, such as mastitis. However, although antibiotics will resolve breast infection, they cannot treat IBC. If your doctor prescribes antibiotics and your symptoms do not resolve within seven to 10 days, this may be a sign that you have IBC. Ibc tends to grow quickly and aggressively and is typically diagnosed when it is already in advanced stage, most often stage IIIB or stage IV. Inflammatory Breast Cancer Treatment options: Treatment of inflammatory Breast Cancer typically includes chemotherapy, followed by Surgery and Radiation therapy. Additional therapy, such as hormone therapy and / or additional chemotherapy, may also be give. Learn more about advanced treatments for Breast Cancer.


Male breast cancer

Male breast cancer occurs when malignant cells form in tissues of the breast. Any man can develop breast cancer, but it is most common among men who are 60 to 70 years old. About 1 percent of all breast cancers occur in men. About 2 000 men are diagnosed with breast cancer each year. Many men may be surprised to learn they can get breast cancer. Men have breast tissue that develops in the same way as breast tissue in women and is susceptible to cancer cells in the same way. In girls, hormonal changes at puberty cause female breasts to grow. In boys, hormones made by testicles prevent breasts from growing. Breast cancer in men is uncommon because male breasts have ducts that are less developed and are not exposed to growth - promoting female hormones. Just like in women, breast cancer in men may begin in ducts and spread to surrounding cells. More rarely, men may develop inflammatory breast cancer or Pagets disease of breast, if a tumor that begins in duct beneath the nipple moves to the surface. Male breasts have few if any lobules, and so lobular carcinoma rarely, if ever, occurs in men. Men should also be aware of gynecomastia, most common male breast disorder. Gynecomastia is not a form of cancer but does cause growth under the nipple or areola that can be felt, and sometimes see. Gynecomastia is common in teenage boys due to hormonal changes during adolescence, and in older men, due to late - life hormonal shifts. Certain medications can cause gynecomastia, as can some conditions, such as Klinefelter syndrome. Rarely, gynecomastia is due to tumor. Any such lumps should be examined by your doctor. Male breast cancer treatment typically consists of mastectomy, followed by radiation therapy, chemotherapy, hormone therapy and / or target therapy. Since many male breast cancers are hormone receptor - positive, drug tamoxifen is often standard therapy for male breast cancer. For men whose cancer has not spread to lymph nodes, adjuvant therapy is generally the same as for women with breast cancer. For men whose cancer has spread to lymph nodes, adjuvant therapy may include chemotherapy plus tamoxifen and / or other hormone therapy. Treatment for men with cancer that has spread to other parts of the body may include hormone therapy and / or chemotherapy.


What kind of treatment will I need?

Youll be glad when treatment is over. But it is hard not to worry about cancer coming back. Even if cancer never comes back, people still worry about it. For years after treatment ends, you will see your cancer doctor. Be sure to go to all of these follow - up visits. You will have exams, blood tests, and maybe other tests to see if cancer has come back. First, your visits may be every 3 to 6 months. Then, longer youre cancer - free, less often visits are needed. After 5 years, they may be do once a year. If you still have breast, you need to get a mammogram every year. You cant change the fact that you have cancer. What you can change is how you live the rest of your life - making healthy choices and feeling as well as you can.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

Sources

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