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Marfan Syndrome

Summarized by Plex Health
Last Updated: 02 May 2022

Marfan syndrome is a disorder that influences the connective tissue in many parts of the body. The two primary features of Marfan syndrome are vision troubles triggered by a dislocated lens in one or both eyes and issues in the large capillary that distributes blood from the heart to the remainder of the body. Stretching of the aorta may cause the aortic shutoff to leak, which can lead to unexpected tearing of the layers in the aorta wall. Many individuals with Marfan syndrome have additional heart troubles including a leak in the valve that attaches two of the 4 chambers of the heart or the shutoff that controls blood circulation from the heart into the aorta. Most individuals with Marfan syndrome have some level of nearsightedness. Clouding of the lens may occur in mid-adulthood, and increased pressure within the eye takes place more often in people with Marfan syndrome than in those without the problem. Some difficulties of Marfan syndrome can be very major, like an aneurysm of the aorta, the main artery that takes blood far from the heart. Marfan syndrome is rare, taking place in about 1 in 5,000 people. Marfan syndrome is triggered by a mutation in a genetics called FBN1. One in four people with Marfan syndrome develops the condition for unidentified reasons. An individual with Marfan syndrome has a 1 in 2 chance of passing it on their child. People that might have Marfan syndrome need to be examined to assist minimize the risk of prospective heart issues. Some people with Marfan syndrome do not reveal signs of it until later on in childhood or in adulthood. Examining for Marfan syndrome might include. Not every person with Marfan syndrome has all of the complications. Some people are only slightly affected by Marfan syndrome, while others develop more major symptoms. The malfunctioning fibrillin genetics causes some bones to grow longer than they should. This means an individual with Marfan syndrome may be tall since their limbs grow longer than normal. Identifying Marfan syndrome can be difficult as the symptoms can vary considerably from individual to person. As the symptoms of Marfan syndrome do not constantly develop throughout youth, it may not be identified till the teen years. A medical diagnosis of Marfan syndrome is based on a thorough physical evaluation and a thorough evaluation of an individual's medical and family background.

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