Medullary cystic kidney disease type 1 is an acquired condition that impacts the kidneys. The kidneys filter fluid and waste items from the body. As MCKD1 advances, the kidneys are less able to function, leading to kidney failure. Decreasing kidney function in people with MCKD1 brings about the symptoms and signs of the condition. Many individuals with MCKD1 develop high blood pressure, especially as kidney function worsens. Some develop high degrees of a waste item called uric acid in the blood because the harmed kidneys are not able to remove uric acid effectively. Although the condition is called medullary cystic kidney disease, only about 40 percent of affected individuals have medullary cysts, which are fluid filled pockets found in a specific area of the kidney. When present, the cysts are usually found in the internal part of the kidney or the border between the external and internal components.
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