Melatonin

Summarized by Plex Health
Last Updated: 03 May 2022

Melatonin is the all-natural hormone your body produces that aids to keep your wake-sleep cycle. Melatonin is additionally made synthetically and readily available over the counter as an over the counter nutritional supplement in the U.S. Supplemental Melatonin has been suggested to have many uses, from rest disorders to cancer treatment, but ample studies are lacking for many uses. All-natural melatonin production begins from the amino acid tryptophan, with serotonin as an intermediary, and then is launched to the receptors in the brain, eye and other areas to help regulate the rest high quality and wake cycles. Taking extra melatonin for rest before going to bed might not be the best method for all rest disorders. You can take a manmade version of melatonin for temporary rest problems. Melatonin is used to treat rest troubles in people aged 55 and over. Some people may get a headache after taking melatonin, or feel tired, cranky or sick the following day. To see to it melatonin is risk-free for you, inform your medical professional if you: have had a sensitive reaction to melatonin or any other medications in the past; have liver or kidney problems; have rheumatoid arthritis, multiple sclerosis or lupus, or any other autoimmune condition. The production and launch of melatonin in the brain is connected to time of day, boosting when it's dark and lowering when it's light. Melatonin production declines with age. Melatonin is offered as a supplement, usually as an oral tablet computer or pill. Most melatonin supplements are made in a laboratory. People typically use melatonin for sleep disorders, such as insomnia and jet lag. Research suggests that melatonin may decrease evening confusion and uneasyness in people with Alzheimer's disease, however it does not seem to enhance cognition.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
896C13H16N2O2232.28CC(=O)NCCC1=CNC2=C1C=C(C=C2)OCCC(=O)NCCC1=CNC2=C1C=C(C=C2)OCInChI=1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)DRLFMBDRBRZALE-UHFFFAOYSA-NN-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide0.8232.121177757232.12117775754.127002241700000001
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