Summarized by Plex Health
Last Updated: 05 May 2022
expression of proto-oncogene kit is up-regulated in subset of human meningiomas. "expression of proto-oncogene kit is up-regulated in subset of human meningiomas.", by Saini M, Jha AN, Abrari A, Ali S. F1: Immunoexpression of KIT in meningioma and control samples. (A-G) Immunohistochemical staining results (A) GIST (positive control) showing strong immunopositivity with membranous staining (black arrow), (B) an otherwise KIT negative meningioma showing interspersed positive mast...

A meningioma is a tumor that emerges from the meninges, the membrane layers that border the brain and spinal cord. Meningioma is one of the most common type of tumor that forms in the head. Most meningiomas grow very gradually, often over several years without creating symptoms. Occasionally, their impacts on close-by brain tissue, nerves or vessels may cause serious handicap. Meningiomas occur more frequently in women and are frequently discovered at older ages, yet they may occur at any age. Most signs and symptoms of a meningioma develop slowly, but occasionally a meningioma calls for emergency treatment. Make a visit to see your health and wellness treatment provider if you have consistent symptoms and signs that concern you, such as headaches that intensify over time. Back of the brain, loss of half of the line of vision in one eye. Compression, the tumour may be large sufficient to squash the underlying brain tissue. Irritation, the nerves of the brain may be irritated and interfered with by the tumour's existence, especially if the tumour is located over the cortex. Seizures are a common symptom of cortex irritation. Invasion, the tumor might invade brain tissue. Symptoms rely on which components of the brain are affected. Injuries to blood vessels, the tumor might disrupt blood flow to different components of the brain by harming or obstructing the capillary. High quality tumors can develop on their own or arise from the malignant development of lower grade tumors. Hearing loss can occur if the tumor is located at the junction between the brain and a region of the brainstem referred to as the pons. A tumor located in the opening of the skull where the spinal cord gets in touch with the brainstem can also lead to limb weakness. Compression from a meningioma can additionally harm cerebrospinal liquid drain and lead to build-up of cerebrospinal liquid in the brain, a problem referred to as hydrocephalus.

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