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Mercaptopurine

Summarized by Plex Health
Last Updated: 02 May 2022
harmful effects of the azathioprine metabolite 6-mercaptopurine in vascular cells: induction of mineralization. "harmful effects of the azathioprine metabolite 6-mercaptopurine in vascular cells: induction of mineralization.", by Prüfer J, Schuchardt M, Tölle M, Prüfer N, Höhne M, Zidek W, van der Giet M. pone-0101709-g001: 6-MP-induced calcification in vitro and ex vivo.(A–D) VSMCs were cultured in control medium or CM±6-MP (100 µmol/L) for 21 days. (A) Mineral deposits were visualized via Alizarin red staining. One representative experiment is shown...

Mercaptopurine is used to treat severe lymphoblastic or lymphocytic leukemia. Mercaptopurine is in some cases supplied other cancer medications. You should not use mercaptopurine if you have ever used mercaptopurine or thioguanine and they were not effective in treating your condition. Some people utilizing mercaptopurine have established unusual fast-growing type of lymphoma. The fluid is pink to brownish in shade with a raspberry taste. 2 enzymes in the body called thiopurine methyltransferase and nudix type motif 15 have the capacity to damage down certain medicines, including mercaptopurine. A hereditary test can be done to identify just how well your TPMT and NUDT15 enzymes damage down medicines. You ought to obtain lower dosages of mercaptopurine if your body breaks down the medicine slower than most people. This medicine may be harmful to the unborn child. Call among your caretakers at St. Jude if you are sexually active or think you might be pregnant. Definition from the NCI Drug Dictionary, Detailed scientific definition and other names for this drug. Drugs are commonly studied to discover out if they can help deal with or stop conditions besides the ones they are approved for. This patient info sheet uses only to approved uses of the medication. Nonetheless, much of the info may additionally relate to unauthorized uses that are being studied. Discover Clinical Trials for Mercaptopurine, Check for trials from NCI's checklist of cancer medical trials now approving patients.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
667490C5H4N4S152.18C1=NC2=C(N1)C(=S)N=CN2C1=NC2=C(N1)C(=S)N=CN2InChI=1S/C5H4N4S/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10)GLVAUDGFNGKCSF-UHFFFAOYSA-N3,7-dihydropurine-6-thione0152.01566732152.0156673285.219002201000000001
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