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Metformin

Summarized by Plex Health
Last Updated: 03 May 2022
effect of metformin on the human t98g glioblastoma multiforme cell line. "effect of metformin on the human t98g glioblastoma multiforme cell line.", by Ucbek A, Ozünal ZG, Uzun O, Gepdıremen A. f3-etm-07-05-1285: Ethidium bromide and acridine orange fluorescein dye in the T98G cell line (magnification ×400). Apoptotic cells are indicated with an arrowhead. (A) Control, (B) 2.5 mM H2O2, (C) 1 mM metformin, (D) 1 mM...

Metformin is an oral diabetes medicine that helps control blood glucose degrees. Metformin is used along with diet regimen and workout to improve blood glucose control in adults with type 2 diabetes mellitus. Metformin is occasionally used along with insulin or other medications, however it is except treating type 1 diabetes. Metformin is additionally used off-label to treat polycystic ovary syndrome. You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. Managing diabetes is very essential while pregnant, and having high blood glucose may cause complications in both the infant and the mother. If you come to be pregnant while taking metformin, inform your medical professional. Some forms of metformin are taken only once daily with the night meal. Type 2 diabetes is a condition where the body does not make enough insulin, or the insulin that it improvises not work correctly. Metformin reduces your blood sugar degrees by enhancing the way your body deals with insulin. Not every person gets diabetes symptoms, so taking metformin may not make you really feel any various. It's best to take metformin with a meal to decrease the side effects. If you have diabetes, you can secure free prescriptions for all of your medications, not just your diabetes ones. With this type of diabetes, insulin produced by the pancreas is unable to get sugar into the cells of the body where it can work effectively. Using metformin alone, with a type of oral antidiabetic medicine called a sulfonylurea, or with insulin, will aid to lower blood sugar level when it is too high and help bring back the way you use food to make energy. Many individuals can regulate type 2 diabetes with diet plan and exercise. Metformin does not help patients that have insulin-dependent or type 1 diabetes because they can not generate insulin from their pancreas gland.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
4091C4H11N5129.16CN(C)C(=N)N=C(N)NCN(C)C(=N)N=C(N)NInChI=1S/C4H11N5/c1-9(2)4(7)8-3(5)6/h1-2H3,(H5,5,6,7,8)XZWYZXLIPXDOLR-UHFFFAOYSA-N3-(diaminomethylidene)-1,1-dimethylguanidine-1.3129.10144537129.1014453791.51320312900000001
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