Microphthalmia is an eye irregularity that develops prior to birth. In some affected individuals, the eyeball may seem totally missing out on; however, even in these cases some remaining eye tissue is normally present. Such severe microphthalmia should be differentiated from another problem called anophthalmia, in which no eyeball forms whatsoever. Microphthalmia might or might not lead to substantial vision loss. People with microphthalmia might additionally have a problem called coloboma. Colobomas are missing items of tissue in frameworks that create the eye. People with microphthalmia might have other eye problems, consisting of clouding of the lens of the eye and a narrowed opening of the eye. Between one-third and half of affected people have microphthalmia as part of a disorder that influences other organs and cells in the body.
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