Midazolam
Summarized by Plex Health
Last Updated: 02 May 2022
"midazolam anesthesia protects neuronal cells from oxidative stress-induced death via activation of the jnk-erk pathway", by . f2-mmr-15-01-0169: Effects of midazolam on intracellular ROS generation in oxidative stress-induced cortical neuronal cells. (A) ROS generation was measured using the H2DCFDA assay. Cortical neuronal cells were treated with BSO/H2O2 and midazolam for 24 h....
Midazolam is a benzodiazepine that is used to assist you relax prior to having a small surgery, dental work, or other medical treatment. Midazolam might be used for purposes not noted in this drug overview. Midazolam can slow or quit your breathing, particularly if you have lately used an opioid medication or alcohol. Midazolam is usually given as a single dosage prior to your surgical procedure or treatment. Midazolam can slow or stop your breathing, especially if you have just recently used an opioid medicine or alcohol. After you take midazolam, you will be watched closely to make certain the medicine is functioning and does not cause harmful side effects.
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PubChem - CovalentUnitCount
(Table source)| CID | MolecularFormula | MolecularWeight | CanonicalSMILES | IsomericSMILES | InChI | InChIKey | IUPACName | XLogP | ExactMass | MonoisotopicMass | TPSA | Complexity | Charge | HBondDonorCount | HBondAcceptorCount | RotatableBondCount | HeavyAtomCount | IsotopeAtomCount | AtomStereoCount | DefinedAtomStereoCount | UndefinedAtomStereoCount | BondStereoCount | DefinedBondStereoCount | UndefinedBondStereoCount | CovalentUnitCount |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 4192 | C18H13ClFN3 | 325.8 | CC1=NC=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4F | CC1=NC=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4F | InChI=1S/C18H13ClFN3/c1-11-21-9-13-10-22-18(14-4-2-3-5-16(14)20)15-8-12(19)6-7-17(15)23(11)13/h2-9H,10H2,1H3 | DDLIGBOFAVUZHB-UHFFFAOYSA-N | 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine | 2.5 | 325.0782033 | 325.0782033 | 30.2 | 471 | 0 | 0 | 3 | 1 | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
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