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Mmr Vaccine For Covid 19

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Last Updated: 02 July 2021

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General | Latest Info

Friday, Sept. 4 2020 - New clinical trial will try to determine whether Measles, mumps and Rubella vaccine can protect health care workers from being infected with COVID - 19. Hundreds of millions of people have received the MMR vaccine since it was developed nearly 50 years ago. It's usually given to children before age 6. Growing evidence suggests that vaccines may also prevent COVID - 19. We know that the MMR vaccine is safe, and we think there are two main reasons that it could prevent COVID - 19, say researcher Dr. Michael Avidan, head of the Department of Anesthesiology at Washington University School of Medicine Louis. First is this vaccine includes small amounts of live but very weakened Measles, mumps and Rubella viruses, Avidan explains in a University news release. This type of vaccine appears to strengthen the body's immune response to infections in general, not just to viruses in that particular vaccine. Mmr vaccine may also work because it protects against viruses that are similar to the Coronavirus. Researchers think that antibodies made to MMR vaccine might also fight SARS - CoV - 2. In addition, researchers hope that the MMR vaccine might make cases of COVID - 19 milder. The Trial is funded by a 9 million grant from the Bill and Melinda Gates Foundation, Wellcome Trust, Mastercard, and other public and philanthropic donors. Researchers hope to enroll as many as 30 000 health care workers around the world. Participants will be randomly selected to get the MMR vaccine or placebo. Most of those recruited for trial will receive booster, as they likely received vaccine as children. But in some countries where MMR vaccine isn't widely give, health care workers may be receiving vaccine for the first time, researchers note. Countries involved in study include Canada, Ghana, Ireland, South Africa, Uganda, United Kingdom, United States, Zambia and Zimbabwe. Each study participant will be followed for five months, and the entire trial is expected to last about a year, researchers say. Scientists at University College London will compile data from the trial.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

Abbreviations

The ISMP National Vaccine Errors Reporting Program contains many cases of repetitive mix - ups between Vaccines that reporters felt were caused by similar abbreviations or acronyms. For example, recent report involves confusion between Hib and HPV. During an office visit, healthcare practitioner administered 9vHPV to a 2 - month - old baby who was supposed to receive Hib. This is not the first report of a mix - up between these two vaccine abbreviations, but it is the first that involved infant. We contacted Merck, manufacturer. Understandably, company was unable to provide information about adverse effects on infants. Searching the ISMP VERP database from September 2012 to February 2017, most frequently reported mix - ups among Vaccine abbreviations or acronyms involve: Tdap and DTaP DT and Td MMR and MMRV PCV13 and PPV23, or PCV and PPV Hib and HepB HepA and HepB DTaP - HepB - IPV, DTaP - IPV / Hib, and DTaP - IPV HPV and IPV HPV and HBV MCV and PCV MCV and MMR VAR and HZV IPV and PPD IIV and PPD PCV and PPD HPV and Hib MMRV and MPSV HepA and HPV4 HepB and HPV4 group of abbreviations use for tetanus, diphtheria, and pertussis were most frequently confused Vaccine abbreviations or acronyms in ISMP VERP database. Similar findings are well documented in various studies and analyses of Vaccine Errors. 1 - 4 However, we have also received more than a dozen reports of mix - ups between abbreviations used for pneumococcal Vaccines, and Measles, mumps, and Rubella Vaccines with and without varicella component. Vaccine labeling and packaging may contribute to mix - ups because distinguishing factors, such as noting intend vaccine age group, are not always prominent on label or are poorly position, as with DTaP and Tdap, and DT and Td. Also, federal requirement to list full nonproprietary name, which is often very long, above brand name on Vaccine packaging makes it hard to read labels and contributes to similarities if Vaccine components overlap. Errors caused by unclear vaccine abbreviations have been a longstanding problem. More than a decade ago, ISMP surveyed health professionals about errors relating to vaccine abbreviations. 5 Almost half of survey respondents experienced errors stemming from Vaccine abbreviations used in handwritten orders; one in three encountered errors with abbreviations used on Immunization records; one in four reported that abbreviations on Vaccine protocols or schedules had contributed to errors; and almost one in five were aware of Errors that result from Vaccine abbreviations use on pharmacy labels or manufacturers product labels. While 63% of respondents believe standard abbreviations should be used for vaccines, only 55% believe this would reduce the risk of errors. Problems continue to worsen as new vaccines are added to the arsenal. Please keep in mind that reports submitted to ISMP VERP likely represent just the tip of the iceberg. Clearly, use of vaccine abbreviations and acronyms, even those that are standardize, is contributing to errors.


What does MMR mean?

Also, you should not become pregnant for one month after having rubella immunisation. It is safe, however, to have if you are breast - feeding. If you are having chemotherapy or if your immune system is suppressed for other reasons. If you are seriously ill, you should postpone the vaccine until you are better. However, if the illness is minor, vaccine need not be delay. The typical example is a child who gets tummy bug or earache on the day the vaccine is due. Providing they do not have a temperature and are well themselves, injection can be give. If you are allergic to medicines, neomycin or gelatin. There is a version of vaccine available which does not contain gelatin if you are allergic to, or prefer not to have, gelatin. Note: if you are allergic to eggs, you may receive the vaccine safely.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

Training the immune system

The type of vaccines that have effect against unrelated infectious are called live attenuate vaccines. This means they contain real viruses or bacteria that scientists have weakened in the laboratory. Studies show that these vaccines protect against other infections by training the immune system in a non - specific way. This type of non - specific immune response is the first line of defense against infection and is called innate immune Response. Live attenuated vaccines seemingly have some nonspecific benefits as well as immunity to target pathogen,s explains co - author of the new paper Dr. Paul Fidel, Jr., Associate Dean for Research at Louisiana State University Health School of Dentistry in New Orleans. Dr. Fidel, together with Dr. Mairi Noverr, Professor of Microbiology & Immunology at Tulane University School of Medicine in New Orleans, suggest that protection afforded by these vaccines is due to myeloid - derive suppressor cells, or MDSCs, type of immune cell that come from bone marrow. Scientists have shown that these cells can reduce inflammation and mortality in mouse models of infection. In their own research, Drs. Fidel and Noverr have shown that vaccination with live - attenuate fungus may protect against sepsis thanks to MDSCs.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

The evidence behind the theory

Fidel and Noverr say the MMR vaccine could induce MDSCs in people with COVID - 19, which could help them to fight lung inflammation and sepsis associated with most severe forms of disease. As evidence for this, they cite a recent case where 955 sailors on USS Roosevelt tested positive for COVID - 19 but only experienced mild symptoms. Researchers suggest that this may be because all US Navy recruits receive MMR vaccination. However, it is likely that age and fitness of sailors also play a part in their recovery. Other evidence in support of the connection between the MMR vaccine and COVID - 19 recovery come from epidemiological data. People WHO live in areas that routinely receive MMR vaccine have lower COVID - 19 death rates. Covid - 19 is also less likely to affect children, which may also have links to vaccination. While age is a known risk factor for COVID - 19 severity, fact that many children have had more recent exposure to live attenuated vaccines could also play a role in their protection, article suggest.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

Progressing to clinical trial

Covid - 19 is a disease caused by the novel betacoronavirus, severe acute respiratory Syndrome Coronavirus 2. The disease was first reported in December 2019 in Wuhan, China and the full genome was sequence and published by January 05 2020. By March 11 2020, COVID - 19 had spread globally and was declared pandemic, with, at time of writing, June 6 2020, there had been over 6 million people infected and 380 000 deaths. Diseases primarily affect respiratory tract and disease severity can range from very mild rhinorrhoea to severe acute respiratory distress Syndrome and death,. Non - respiratory symptoms such as anosmia, diarrhoea, rash, thromboembolic disorders, myocarditis and vasculitis have also been associated with COVID - 19,. The median incubation period is estimated to be 5 days with the majority developing symptoms by 11. 5 days. Covid - 19 patients have been shown to excrete viral nucleic acid at highest levels at onset of symptoms. This, and other epidemiological data suggest transmissibility within as yet undefined pre - symptomatic period. Clinical deterioration is usually delayed into the second week of illness and associated with laboratory features of immune - mediate cytokine storm causing widespread inflammation and disseminate intravascular coagulation, usually with low level viraemia,. The case fatality rate is consistently reported to be age dependent, with a higher percentage of elderly cases dying, although other factors are also associated with intensive care admission and mortality, including sex, hypertension, obesity and diabetes. Report case fatality rates have been between 0. 82% and 9. 64%, with variability in CFR likely due to testing frequency and access as well as other health system capacity factors in different locations. The Infection fatality rate is a better estimate of population mortality and is modelled to be between 0. 1% and 0. 41%. Sars - CoV - 2 is one of three coronaviruses that may cause severe respiratory diseases, including fatality, in humans and has been associated with major outbreaks in the last 20 years;. The other two viruses are severe acute respiratory Syndrome Coronavirus and Middle East respiratory Syndrome Coronavirus. Although there were some attempts at development of vaccines against SARS and MERS, including a small number of human Phase 1 clinical trials, there are no licenced vaccines for any Coronavirus as yet. In addition to these novel Epidemic viruses with zoonotic origins, there are four other endemic human coronaviruses in circulation, HCoV2 - 229E, - HKU1, - NL63 and - OC43 all predominantly causing mild symptoms of common cold.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

REPLY

On a sunny day in May, Bun Sreng Sineth and other immunization staff set up an immunization site in the Muslim community in Phnom Penh Mekong Operational District. On the banks of the Mekong River, children and their caregivers gather in tents to be immunized and to learn how to prevent COVID - 19. Sineth and her colleagues were responding to two disease outbreaks: measles outbreak, and the COVID - 19 pandemic. In January 2020, as Cambodia confirmed its first COVID - 19 case, it also confirmed 84 cases of measles. I am really happy that the government continue these outreach vaccination services, Sineth said after the final child had received his immunization. She felt confident in her ability to continue administering immunizations safely, largely because of information she had received from the Ministry of Health and World Health Organization. Measles is a highly contagious and serious disease that has surged in recent years. Globally, November 2019 saw the greatest numbers of measles cases recorded since 2006. And although Cambodia received its measles elimination status in 2015, following years of hard work by government and health partners like WHO, it has not been immune to global measles resurgence. From 1 January to 4 May 2020, Cambodia recorded 341 measles cases, significant increase from 44 cases recorded during the same period in 2019. Of these 341 Cambodians, 65% had not been vaccinate. During pandemic, it was more important than ever to maintain routine immunization services to protect children and the community, say Dr Li Ailan, WHO Representative to Cambodia. Otherwise, risk of vaccine - preventable disease outbreaks would increase, and especially the risk of uncontrollable measles outbreak.S Along with measles, Cambodia was in the midst of rubella and pertussis outbreaks. It was critical that children receive immunizations to prevent them from contracting these diseases, and to prevent additional strain from being placed on the public health system during the COVID - 19 pandemic. Bun Sreng Sineth, far right, and other Immunization staff clean their hands before administering immunizations at the mobile Immunization site in Phnom Penh. Who / Theng Vanpiseth in 2000, Cambodia's Ministry of Health established the National Immunization Program to expand Cambodia Immunization services. The programme promotes the well - being of all Cambodians by controlling, eliminating or eradicating target vaccine - preventable diseases. Nip, WHO, UNICEF and other partners work together closely to coordinate programmes immunization activities. In March, as more cases of COVID - 19 were reported in country, WHO supported development of interim guidance for NIP on how to safely continue its immunization activities and risk management plan on how to respond to measles outbreak during the COVID - 19 pandemic. This guidance also outlines the role of NIP Immunization staff in responding to COVID - 19. Because of this staunch commitment and careful planning on how to continue lifesaving immunizations, routine immunization was sustained throughout the pandemic. Most Cambodians are immunized at health centres and hospitals, which conduct routine immunizations according to regular immunization schedules.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

Sources

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

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