Moxetumomab Pasudotox

Summarized by Plex Health
Last Updated: 04 May 2022

Moxetumomab pasudotox-tdfk is made up of a recombinant, murine immunoglobulin variable domain genetically integrated to a truncated type of Pseudomonas exotoxin, PE38, that hinders protein synthesis. Moxetumomab pasudotox-tdfk has an approximate molecular weight of 63 kDa and is produced in E. coli cells by recombinant DNA modern technology. LUMOXITI for shot is supplied as a sterile, preservative-free, white to beige lyophilized cake or powder in a single-dose vial for reconstitution and dilution before intravenous mixture. After reconstitution with 1. 1 mL Sterile Water for Injection, USP, the resulting 1 mg/mL option allows a withdrawal volume of 1 mL. Prior to intravenous mixture, the reconstituted vial of remedy are included in an infusion bag having 50 mL of 0. 9% Sodium Chloride Injection, USP and 1 mL of IV Solution Stabilizer. IV Solution Stabilizer is a sterile, preservative-free, anemic to slightly yellow, clear remedy devoid of visible bits and supplied in a single-dose vial. The LUMOXITI and IV Solution Stabilizer vial stoppers are not made with natural rubber latex.

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