Summarized by Plex Health
Last Updated: 04 May 2022
fxr antagonism of nsaids contributes to drug-induced liver injury identified by systems pharmacology approach. "fxr antagonism of nsaids contributes to drug-induced liver injury identified by systems pharmacology approach.", by Lu W, Cheng F, Jiang J, Zhang C, Deng X, Xu Z, Zou S, Shen X, Tang Y, Huang J. f2: The NSAID-SE association network.In the network, nodes represent NSAIDs (Non-steroidal anti-inflammatory drug, green circles) and side effects (SE, gold squares) that were caused by at least 10 different NSAIDs, and where edges represent clinically...

Non-steroidal anti-inflammatory drugs are medicines extensively used to ease pain, decrease inflammation, and reduce a high temperature. The majority of people can take NSAIDs, but some people require to be careful about taking them. It's a good suggestion to ask a pharmacist or doctor for recommendations before taking an NSAID if you: are over 65 years of age; are pregnant or trying for an infant; are nursing; have bronchial asthma; have had an allergy to NSAIDs in the past; have had stomach abscess in the past; have any problems with your heart, liver, kidneys, high blood pressure, blood circulation, or bowels; are taking other drugs, see communications with other medications; are looking for drug for a child under 16, any medicine that has pain killers ought to not be offered to children under 16. NSAIDs may be offered or recommended under these names or a trademark name. NSAIDs have long been a mainstay for migraine management. The best-known NSAIDs used for acute migraine headache treatment are advil and naproxen salt, both offered over the counter and by prescription. There is also evidence that pain killers may be a reliable migraine therapy. Triptans are usually the first treatment advised for moderate to extreme migraine attacks in patients. In the couple of studies that have compared a particular NSAID with a triptan, the NSAID has done at least virtually. Co-administration of an NSAID and an oral triptan may be more reliable than taking either medicine alone. If used more than 10 to 15 days per month, most NSAIDs can lead to medication overuse headache.

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PubChem - CovalentUnitCount

(Table source)
53789754C9H10N4O4238.20C1=CC(=CC=C1C(N=C(N)N)[N+](=O)[O-])C(=O)OC1=CC(=CC=C1C(N=C(N)N)[N+](=O)[O-])C(=O)OInChI=1S/C9H10N4O4/c10-9(11)12-7(13(16)17)5-1-3-6(4-2-5)8(14)15/h1-4,7H,(H,14,15)(H4,10,11,12)FAZSDZKUUAFTNR-UHFFFAOYSA-N4-[(diaminomethylideneamino)-nitromethyl]benzoic acid0238.07020481238.0702048114832603531701010001
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