Nager Syndrome

Summarized by Plex Health
Last Updated: 03 May 2022

Nager syndrome is uncommon condition that generally impacts the advancement of the face, hands, and arms. Children with Nager syndrome are born with underdeveloped cheek bones and a very small lower jaw. These problems often cause feeding problems in infants with Nager syndrome. People with Nager syndrome commonly have eyes that incline downward, no eyelashes, and a notch in the lower eyelids called an eyelid coloboma. Many affected individuals have small or abnormally formed ears, and about 60 percent have hearing loss brought on by defects in the center ear. Nager syndrome does not impact a person's intelligence, although speech advancement may be delayed due to hearing impairment. Individuals with Nager syndrome have bone irregularities in their hands and arms. Affected individuals might also have fingers that are unusually bent or merged together. People with Nager syndrome occasionally have problem fully extending their joints. This problem can cause bone irregularities in the legs and feet.

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