Neurofibromatosis

Summarized by Plex Health
Last Updated: 02 May 2022
medpix case - neurofibromatosis-1 "medpix case - neurofibromatosis-1", by Original Source: David Hsieh; Author: MS-4 USU Teaching File (Uniformed Services University); Approved By: James G. Smirniotopoulos, M.D. (Uniformed Services University);. Extensive plexiform neurofibromas in S-Spine and lower extremities...

Neurofibromatosis is a genetic disorder of the nervous system. Tumors, or neurofibromas, grow along the body's nerves or on or beneath the skin. Scientists have classified NF into two unique types: neurofibromatosis type 1 and NF2. NF1, formerly understood as von Recklinghausen's NF, is the more common of the types. It takes place in roughly 1 in 4,000 births. NF2, described as reciprocal acoustic NF, central NF or vestibular NF, occurs less often- 1 in 40,000 births. Incidents of NF1 and NF2 are present among all racial groups and influence both sexes similarly. The tumors occur from changes in the nerve cells and skin cells. Tumors additionally might continue the body's important areas as their size increases. NF might lead to developmental abnormalities and/or increased possibilities of having learning impairments. Other forms of NF, where the symptoms are not regular keeping that of NF1 or NF2, have been observed. An unusual type of NF is schwannomatosis. The genetic cause of this form of NF has not been found.

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