Noonan Syndrome with Multiple Lentigines

Summarized by Plex Health
Last Updated: 10 May 2022

Noonan syndrome with multiple lentigines is a condition that impacts many areas of the body. As the problem name suggests, Noonan syndrome with multiple lentigines is very similar to a problem called Noonan syndrome, and it can be hard to inform both disorders apart in early childhood. Not all people with Noonan syndrome with multiple lentigines have all the particular features of this condition. Affected individuals may have thousands of small dark brownish skin areas by the time they reach adolescence. Of individuals with Noonan syndrome with multiple lentigines who have heart defects, about 80 percent have hypertrophic cardiomyopathy, which is a thickening of the heart muscular tissue that requires the heart to work harder to pump blood. Approximately 20 percent of people with Noonan syndrome with multiple lentigines who have heart issues have a narrowing of the artery from the heart to the lungs. People with Noonan syndrome with multiple lentigines can have unique face look. At birth, people with Noonan syndrome with multiple lentigines are normally of normal weight and height, yet in some, growth slows down in time. This slow development results in affected people being much shorter than standard, although less than fifty percent of people with Noonan syndrome with multiple lentigines have dramatically short stature. Females with Noonan syndrome with multiple lentigines may have badly created ovaries and delayed the age of puberty. Noonan syndrome with multiple lentigines is one of a group of relevant problems collectively understood as RASopathies.

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