ORF

"the orf59 dna polymerase processivity factor homologs of old world primate rv2 rhadinoviruses are highly conserved nuclear antigens expressed in differentiated epithelium in infected macaques.", by Bruce AG, Bakke AM, Gravett CA, DeMaster LK, Bielefeldt-Ohmann H, Burnside KL, Rose TM. F6: The RV2 ORF59 proteins are highly expressed during RV2 rhadinovirus infections of RPFF and Vero cells and localize to the nucleus. Subconfluent cell cultures were infected with either RRV or MneRV2, and ORF59 expression...

Orf is a skin infection you can obtain from infected sheep or goats. Orf is a virus that primarily influences young lambs and goats. You're most in jeopardy if you have routine call with lamb or goats, for instance, if you're a farmer or if you bottle feed a lamb. Orf causes scabs around the animal's nose and mouth, which may infect their teats and legs. Sheep and goats can be vaccinated against the orf virus. People can get contaminated if they come into contact with lately vaccinated or unvaccinated pets. It's very unusual for orf to be passed from someone to another. Orf usually affects the skin on your fingers, hands, forearms or face. If you have brownish or black skin, the spot of skin may look darker. Other symptoms of orf consist of: a high temperature; basic fatigue; inflamed glands on the inside of your arm joint or under your arm.

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