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Ofloxacin

Summarized by Plex Health
Last Updated: 02 May 2022
diffusion of ofloxacin in the endocarditis vegetation assessed with synchrotron radiation uv fluorescence microspectroscopy. "diffusion of ofloxacin in the endocarditis vegetation assessed with synchrotron radiation uv fluorescence microspectroscopy.", by Batard E, Jamme F, Villette S, Jacqueline C, de la Cochetière MF, Caillon J, Réfrégiers M. pone-0019440-g005: Fluorescence of control (A) and ofloxacin-treated (B,C,D) vegetation in the 510–560 nm range.Transmission (left) and fluorescence (right) images. The bacterial masses imaged on maps B, C and D located respectively in the intermediate, peripheral...

Ofloxacin otic remedy, 0. 3% is a clean and sterile liquid anti-infective option for otic use. Chemically, ofloxacin has three condensed 6-membered rings comprised of a fluorinated carboxyquinolone with a benzoxazine ring. The chemical name of ofloxacin is: -9 fluoro-2,3-dihydro-3methyl-10-7oxo-7H-pyrido [1,23-de] -1,4-benzoxazine-6carboxylic acid. The molecular formula of ofloxacin is C18H20FN3O4 and its molecular weight is 361. 37. It is soluble in antarctic acetic acid; sparingly soluble in chloroform and in 0. 1 N sodium hydroxide; moderately soluble to slightly soluble in methylene chloride; a little soluble in dimethylformamide and very somewhat soluble in methyl alcohol and water. Ofloxacin otic remedy has 0. 3% ofloxacin, USP with benzalkonium chloride, salt chloride, and water for shot. Ofloxacin is additionally used to treat pelvic inflammatory disease and Chlamydia and/or gonorrhea. Fluoroquinolone prescription antibiotics can cause disabling or serious side effects that might not be reversible. Ofloxacin might be used for purposes not noted in this medication guide. Ofloxacin might cause swelling or tearing of a tendon, specifically in the Achilles' tendon of the heel. Use ofloxacin for the full prescribed length of time, even if your symptoms rapidly boost. Take the medicine as soon as you can, but miss the missed dose if it is practically time for your following dose. It may additionally be used for other troubles as identified by your medical professional. Ofloxacin may mask or postpone the symptoms of syphilis. It is ineffective versus syphilis infections. Ofloxacin belongs to the course of drugs referred to as fluoroquinolone anti-biotics. It works by killing germs or avoiding their growth. Nonetheless, this medicine will not work for colds, flu, or other virus infections. This medication is available only with your medical professional's prescription.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
4583C18H20FN3O4361.4CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)OCC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)OInChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)GSDSWSVVBLHKDQ-UHFFFAOYSA-N7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid-0.4361.14378429361.1437842973.363401822601010001
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