Parkinson's Disease

Summarized by Plex Health
Last Updated: 01 May 2022
dopaminergic modulation of motor network dynamics in parkinson's disease. "dopaminergic modulation of motor network dynamics in parkinson's disease.", by Michely J, Volz LJ, Barbe MT, Hoffstaedter F, Viswanathan S, Timmermann L, Eickhoff SB, Fink GR, Grefkes C. awu381-F5: Dopaminergic effects on connectivity and behaviour in patients with Parkinson’s disease. (A) Difference in endogenous connectivity between patients with Parkinson’s disease ON (PD-ON) and OFF medication (PD-OFF). Green arrow indicates a significantly increased connectivity...

Parkinson's disease is a type of movement disorder. It occurs when nerve cells in the brain don't create sufficient of a brain chemical called dopamine. Exposure to chemicals in the environment could play a role. They include: Trembling of hands, arms, legs, jaw and face; Stiffness of the arms, legs and trunk; Slowness of movement; Poor equilibrium and coordination. As symptoms become worse, people with the disease might have problem strolling, chatting, or doing easy tasks. PD usually begins around age 60, however it can begin earlier. A selection of medications often aid symptoms drastically. Surgical procedure and deep brain stimulation can help severe cases. Professionals with PD who were exposed to herbicides throughout their service may be qualified for special needs compensation and wellness treatment. In 2021, VA added irregular Parkinsonism to the list of conditions presumably associated with Agent Orange exposure. Irregular Parkinsonism describes a group of diseases with Parkinson's-like symptoms that do not respond well to drug treatment. The partnership has three primary goals: to increase accessibility to PD details, resources, and providers; enlighten Veterans and providers on PD management and ideal methods; and aid Veterans navigate Parkinson's-related health and social services. Parkinson's disease is a neurological problem that generally causes shake and/or stiffness in movement. When 3 or more people are affected in a family, especially if they are identified at a very early age we think that there might be a gene making this family more probable to develop the condition. If we meet somebody else that has a non-working duplicate of the same gene and we have a child that inherits 2 non-working copies of that genetics, an issue only emerges. Lots of people affected with PD are not knowledgeable about any relatives with the condition however in a number of families, there is a family background.

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