Partial Androgen Insensitivity Syndrome

"surface rendering of external genitalia of a fetus at the 32nd week of gestation affected by partial androgen insensitivity syndrome.", by Mazza V, Bertucci E, Latella S, Cani C, Ceccarelli P, Iughetti L, Baldinotti F, Percesepe A. fig1: (a) 4D surface rendering female/ambiguous external genitalia; (b) female genitals with oedematous labia majora and mild clitoromegaly; (c) perineal vulvovaginoplasty, clitoroplasty, and gonadectomy....

When the body can't respond to male sex hormones, partial androgen insensitivity syndrome is a genetic problem that takes place. Testosterone is a male sex hormonal agent. PAIS is a type of androgen insensitivity syndrome. Androgen insensitivity syndrome is among the conditions that are referred to as intersex. As a child grows inside the womb, man or female genital areas develop depending on both of sex chromosomes the infant has from the parents. In PAIS, there is a change in the gene on the X chromosome that helps the body recognize and use male hormonal agents effectively. At birth, the infant may have unclear external genitals. If only one copy of the X chromosome lugs the genetic mutation, people with 2 X chromosomes are not affected. Family background is vital in identifying risk factors of PAIS. Breast development in males at the time of puberty; Decreased body and face hair, however normal pubic and underarm hair; Sexual dysfunction and the inability to conceive;.

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