Pemphigus

"medpix case - case 1, (27th annual uniformed services dermatology seminar, 2003) familial benign chronic pemphigus (hailey-hailey disease)", by Original Source: Jason D. Marquart, CRT, MC, USA; Wendy Lee, CDR, MC, USN; Author: James V Twede (Uniformed Services University); Approved By: Leonard C. Sperling (Uniformed Services University);. Scattered crops of erythematous papules with crusting coalescing into plaques without evidence of drainage or foul odor; mild hyperpigmentation at prior crops of lesions; no lymphadenopathy, nail banding, hair, facial, or oral involvement....

Pemphigus is a disease that causes sores and sores on the skin or mucous membranes, such as in the mouth or on the genital areas. Pemphigus can occur at any age, however it's usually seen in people that are middle-aged or older. It often tends to be a lasting problem, and some types can be deadly without treatment. Therapy with medication usually manages it. Pemphigus causes blisters on your skin and mucous membranes. The blisters burst quickly, exposing sores, which may exude and come to be contaminated. Pemphigus is distinct from bullous pemphigoid, which is a scorching skin condition that influences older adults and might cause death. People with the disease produce antibodies versus desmogleins, proteins that bind skin cells to each other. Pemphigus foliaceus normally influences women and men just as, yet in some populations, women get the disease more regularly than men do. Evidence reveals that particular variants in a family of immune system genes called HLA are linked to a higher risk of pemphigus vulgaris and pemphigus foliaceus. Both major forms of pemphigus are: Pemphigus vulgaris is the most common key in the United States. Pemphigus does not spread out from person to individual. Some people's genetics placed them more at risk for pemphigus. Pemphigoid is additionally an autoimmune skin disease. It results in deep sores that do not damage easily. Pemphigoid is most common in older adults and might be fatal for older, sick patients. Medical professionals diagnose pemphigus with a physical examination, a biopsy, and blood tests. These might include: Steroids, which reduce inflammation; Drugs that reduce the body immune system response; Antibiotics to deal with connected infections.

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