Pentamidine

Summarized by Plex Health
Last Updated: 05 May 2022
bisbenzamidine derivative, pentamidine represses dna damage response through inhibition of histone h2a acetylation. "bisbenzamidine derivative, pentamidine represses dna damage response through inhibition of histone h2a acetylation.", by Kobayashi J, Kato A, Ota Y, Ohba R, Komatsu K. F2: The effect of pentamidine on IR-induced cellular response. (A) Pentamidine repressed γ-H2AX foci formation. MRC5SV cells were irradiated with 5 Gy of γ-ray with or without pre-treatment of pentamidine (indicated concentrations, 30 minutes). After...

Pentamidine is an antifungal drug that fights infections brought on by fungus. Pentamidine might additionally be used for purposes not noted in this drug guide. FDA maternity category C. It is not known whether pentamidine will harm a coming child. It is not understood whether pentamidine passes into breast milk or if it could harm a nursing child. Inhaled pentamidine needs to not be provided to a child without the advice of a doctor. Pentamidine is given either as an injection, or as in inhaled medicine using a nebulizer. Pentamidine is a powder medicine that have to be mixed with a liquid before using it as a shot or with a nebulizer. Be certain you recognize exactly how to correctly blend and store the medicine if you are using this medication at home. Inspect your blood sugar thoroughly while you are receiving pentamidine if you are diabetic. This medicine can increase or lower your blood sugar level.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
4735C19H24N4O2340.4C1=CC(=CC=C1C(=N)N)OCCCCCOC2=CC=C(C=C2)C(=N)NC1=CC(=CC=C1C(=N)N)OCCCCCOC2=CC=C(C=C2)C(=N)NInChI=1S/C19H24N4O2/c20-18(21)14-4-8-16(9-5-14)24-12-2-1-3-13-25-17-10-6-15(7-11-17)19(22)23/h4-11H,1-3,12-13H2,(H3,20,21)(H3,22,23)XDRYMKDFEDOLFX-UHFFFAOYSA-N4-[5-(4-carbamimidoylphenoxy)pentoxy]benzenecarboximidamide2.6340.18992602340.18992602118376044102500000001
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