Peroxisomal acyl-CoA oxidase deficiency is a disorder that causes damage of nervous system functions starting in infancy. Newborns with peroxisomal acyl-CoA oxidase deficiency have weak muscle tone and seizures. Added fingers or toes or a bigger liver also occur in some affected people. Most infants with peroxisomal acyl-CoA oxidase deficiency learn to stroll and begin speaking, however they experience a steady loss of these abilities, usually beginning between the ages of 1 and 3. Most children with peroxisomal acyl-CoA oxidase deficiency do not survive previous early childhood years.
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