Pramipexole

Summarized by Plex Health
Last Updated: 02 May 2022
low dose pramipexole is neuroprotective in the mptp mouse model of parkinson's disease, and downregulates the dopamine transporter via the d3 receptor. "low dose pramipexole is neuroprotective in the mptp mouse model of parkinson's disease, and downregulates the dopamine transporter via the d3 receptor.", by Joyce JN, Woolsey C, Ryoo H, Borwege S, Hagner D. F4: Impact of pramipexole on MPTP-induced loss of TH-IR fibers. Low-power photomicrograph (20x) of the caudate-putamen and nucleus accumbens of tissue sections processed for TH-IR from individual cases of 4 groups of mice: (A) Saline-Saline,...

Pramipexole Dihydrochloride Extended-Release Tablets contain pramipexole dihydrochloride. Pramipexole Dihydrochloride Extended-Release Tablets 1. 5 mg: Each extended-release tablet computer contains 1. 5 mg pramipexole dihydrochloride monohydrate equivalent to 1. 41 mg pramipexole dihydrochloride. People with Parkinson's disease might have a higher risk of skin cancer. It is not known whether pramipexole enters breast milk or if it could hurt a nursing child. Your physician may periodically change your dose. The dose and timing of pramipexole in dealing with Parkinson's disease is different from the dose and timing in dealing with RLS. If you are taking this medication for RLS, tell your doctor if your symptoms worsen, if they occur in the early morning or earlier than common at night, or if you really feel troubled symptoms in your arms or hands. Pramipexole is a dopamine agonist that deals with the nervous system to assist treat the symptoms of Parkinson disease. Pramipexole is also used to deal with Restless Legs Syndrome. RLS is a neurologic disorder that influences sensation and movement in the legs and causes the legs to feel awkward. This results in an irresistible feeling of wishing to move your legs to make them comfortable. This medicine is offered only with your physician's prescription.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
119570C10H17N3S211.33CCCNC1CCC2=C(C1)SC(=N2)NCCCN[[email protected]]1CCC2=C(C1)SC(=N2)NInChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)/t7-/m0/s1FASDKYOPVNHBLU-ZETCQYMHSA-N(6S)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine1.9211.11431873211.1143187379.218802431401100001
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