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Praziquantel

Summarized by Plex Health
Last Updated: 02 May 2022
clinical efficacy and tolerability of praziquantel for intestinal and urinary schistosomiasis-a meta-analysis of comparative and non-comparative clinical trials. "clinical efficacy and tolerability of praziquantel for intestinal and urinary schistosomiasis-a meta-analysis of comparative and non-comparative clinical trials.", by Zwang J, Olliaro PL. pntd-0003286-g001: Flow chart of the number of studies and patients screened and eligible for the efficacy analyses of cure rate (CR) and egg reduction rates (ERR).Of the 41 comparative studies identified, 19 directly compared different...

Praziquantel is used to deal with schistosomiasis, also called snail fever or bilharzia, an infection of the urinary tract or bowels, created by schistosoma, a flatworm bloodsucker. It is used to deal with clonorchiasis infection brought on by the Oriental or chinese liver fluke or opisthorchiasis infection caused by the Southeast Asian liver fluke. Blood flukes stay in freshwater snails and are spread out into the bordering waters. You may get contaminated when you get or swim in these waters. They enter the body through the skin and travel up until they reach your bowels where they grow and lay eggs. Occasionally, the eggs get in the liver, which causes persistent inflammation. Infections with a liver fluke usually occur after consuming contaminated undercooked or raw freshwater fish, crabs, or crayfish. Most patients contaminated with liver flukes do disappoint any symptoms, which might cause the infection to last a long time. Praziquantel comes from the family of medications called anthelmintics. Anthelmintics are used in the treatment of worm infections. This medicine is offered only with your physician's prescription.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
4891C19H24N2O2312.4C1CCC(CC1)C(=O)N2CC3C4=CC=CC=C4CCN3C(=O)C2C1CCC(CC1)C(=O)N2CC3C4=CC=CC=C4CCN3C(=O)C2InChI=1S/C19H24N2O2/c22-18-13-20(19(23)15-7-2-1-3-8-15)12-17-16-9-5-4-6-14(16)10-11-21(17)18/h4-6,9,15,17H,1-3,7-8,10-13H2FSVJFNAIGNNGKK-UHFFFAOYSA-N2-(cyclohexanecarbonyl)-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one2.7312.183778013312.18377801340.647200212301010001
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