Pyruvate Dehydrogenase Deficiency

Summarized by Plex Health
Last Updated: 02 May 2022

Pyruvate dehydrogenase deficiency is identified by the buildup of a chemical called lactic acid in the body and a range of neurological issues. People with pyruvate dehydrogenase deficiency usually have neurological issues as well. Some affected individuals have abnormal brain frameworks, such as underdevelopment of the tissue attaching the left and right halves of the brain, atrophying of the exterior part of the brain referred to as the cortex, or spots of harmed tissue on some components of the brain. Because of the extreme health and wellness results, many individuals with pyruvate dehydrogenase deficiency do not endure past childhood years, although some might live into adolescence or adulthood.

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