Quinapril

Summarized by Plex Health
Last Updated: 02 May 2022
stabilization of quinapril by incorporating hydrogen bonding interactions. "stabilization of quinapril by incorporating hydrogen bonding interactions.", by Roy BN, Singh GP, Godbole HM, Nehate SP. F0005: ORTEP view of quinapril tris with atom numbering scheme....

Quinapril hydrochloride is the hydrochloride salt of quinapril, the ethyl ester of a non-sulfhydryl, angiotensin-converting enzyme inhibitor, quinaprilat. Quinapril hydrochloride is chemically referred to as [3S- [2R *], 3R *] -2 [2- [1 -3 phenylpropyl] amino] -1 oxopropyl] -1,234-tetrahydro-3 -isoquinolinecarboxylic acid, monohydrochloride. Its molecular formula is C25H30N2O5HCl and its structural formula is: Quinapril hydrochloride USP is a white to off-white powder, with a pink cast at times that is easily soluble in aqueous solvents. Quinapril tablets, USP include 5 mg, 10 mg, 20 mg, or 40 mg of quinapril for oral administration. Each tablet has colloidal silicon dioxide, crospovidone, hydroxypropyl cellulose, hypromellose, iron oxide red, lactose monohydrate, magnesium carbonate, magnesium stearate, polyethylene titanium, glycol, and povidone dioxide. High blood pressure includes in the workload of the heart and arteries. If it continues for a lengthy time, the heart and arteries might not function properly. Decreasing high blood pressure can reduce the risk of stroke and cardiovascular disease. Quinapril is an angiotensin transforming enzyme inhibitor. Because of this, quinapril relaxes the blood vessels. Quinapril is also used to treat cardiac arrest or may be used for other conditions as identified by your medical professional. This medicine is offered only with your doctor's prescription. You may also require to avoid taking quinapril with aliskiren if you have kidney disease. If you take the medication during your 3rd or 2nd trimester, Quinapril can cause injury or death to the expected baby. If you are being dealt with for high blood pressure, keep making use of quinapril even if you feel well. High blood pressure typically has no symptoms. You may need to use blood pressure medication for the remainder of your life.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
54892C25H30N2O5438.5CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CC3=CC=CC=C3CC2C(=O)OCCOC(=O)[[email protected]](CCC1=CC=CC=C1)N[[email protected]@H](C)C(=O)N2CC3=CC=CC=C3C[[email protected]]2C(=O)OInChI=1S/C25H30N2O5/c1-3-32-25(31)21(14-13-18-9-5-4-6-10-18)26-17(2)23(28)27-16-20-12-8-7-11-19(20)15-22(27)24(29)30/h4-12,17,21-22,26H,3,13-16H2,1-2H3,(H,29,30)/t17-,21-,22-/m0/s1JSDRRTOADPPCHY-HSQYWUDLSA-N(3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid1.2438.21547206438.2154720695.9648026103203300001
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