Quinidine
Summarized by Plex Health
Last Updated: 02 May 2022
-potassium-channels-by-quinine-quinidine-and-barium.png "mechanism of inhibition of mouse slo3 (kca 5.1) potassium channels by quinine, quinidine and barium.")
"mechanism of inhibition of mouse slo3 (kca 5.1) potassium channels by quinine, quinidine and barium.", by Wrighton DC, Muench SP, Lippiat JD. fig05: Molecular modelling of mSlo3 and inhibition by quinidine. (A) Homology model of the transmembrane regions S1 to S6 of mSlo3; the structure is shown as a side-on view from the membrane, with the extracellular...
Quinidine is used to aid keep the heart beating normally in people with particular heart rhythm disorders, usually after other treatments have stopped working. Quinidine is also used to deal with a life-threatening type of malaria. Quinidine might also be used for purposes not noted in this medication guide. quinidine might increase your risk of death, specifically if you have heart issues influencing the cells or shutoffs of your heart. Quinidine can minimize episodes of irregular heart rhythm, this medication may increase your risk of death. If you have heart troubles affecting the tissues or valves of your heart, your risk might be higher. If you are pregnant or plan to come to be pregnant, tell your doctor. Quinidine oral is taken by mouth. When quinidine is offered to treat malaria, you might also be given antibiotic drug. Take the medicine as soon as you can, yet avoid the missed dose if it is almost time for your following dose.
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Research Papers' Summaries
PubChem - CovalentUnitCount
(Table source)| CID | MolecularFormula | MolecularWeight | CanonicalSMILES | IsomericSMILES | InChI | InChIKey | IUPACName | XLogP | ExactMass | MonoisotopicMass | TPSA | Complexity | Charge | HBondDonorCount | HBondAcceptorCount | RotatableBondCount | HeavyAtomCount | IsotopeAtomCount | AtomStereoCount | DefinedAtomStereoCount | UndefinedAtomStereoCount | BondStereoCount | DefinedBondStereoCount | UndefinedBondStereoCount | CovalentUnitCount |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 441074 | C20H24N2O2 | 324.4 | COC1=CC2=C(C=CN=C2C=C1)C(C3CC4CCN3CC4C=C)O | COC1=CC2=C(C=CN=C2C=C1)[[email protected]@H]([[email protected]]3C[[email protected]@H]4CCN3C[[email protected]@H]4C=C)O | InChI=1S/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14-,19+,20-/m0/s1 | LOUPRKONTZGTKE-LHHVKLHASA-N | (S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol | 2.9 | 324.183778013 | 324.183778013 | 45.6 | 457 | 0 | 1 | 4 | 4 | 24 | 0 | 4 | 4 | 0 | 0 | 0 | 0 | 1 |
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