Rifamate

Summarized by Plex Health
Last Updated: 04 May 2022

Rifamate is a combination medication used to deal with tuberculosis. You ought to not use Rifamate if you have active liver disease, or a history of liver problems brought on by taking isoniazid. Serious and in some cases deadly liver issues may occur throughout therapy with Rifamate or after you stop taking this medication, even months after stopping. The risk of liver troubles is greatest in adults between the ages of 35 and 65. Your liver function may require to be inspected every month while you are taking Rifamate. You ought to not use this medication if you are allergic to isoniazid or rifampin, or if you have active liver disease, or a history of liver troubles brought on by taking isoniazid. Serious and often deadly liver troubles may occur during therapy with Rifamate or after you quit taking this medication, even months after quiting. The risk of liver troubles is greatest in adults in between the ages of 35 and 65. Your liver function may require to be examined on a monthly basis while you are taking this medication. It is not recognized whether Rifamate will damage unborn infant. Rifamate can make contraceptive pill less efficient. Ask your medical professional about utilizing non hormone contraception to stop maternity while taking this medicine. Your medical professional will perform blood tests to make certain you do not have conditions that would avoid you from securely utilizing Rifamate. Soft contact lenses may be completely stained if you use them while taking this medication. Your doctor may have you take added vitamin B6 while you are taking Rifamate.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
135483892C49H65N7O13960.1CC1C=CC=C(C(=O)NC2=C(C(=C3C(=C2O)C(=C(C4=C3C(=O)C(O4)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)C=NN5CCN(CC5)C)C.C1=CN=CC=C1C(=O)NNC[[email protected]]1/C=C/C=C(\C(=O)NC2=C(C(=C3C(=C2O)C(=C(C4=C3C(=O)[[email protected]](O4)(O/C=C/[[email protected]@H]([[email protected]]([[email protected]]([[email protected]@H]([[email protected]@H]([[email protected]@H]([[email protected]]1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)/C=N/N5CCN(CC5)C)/C.C1=CN=CC=C1C(=O)NNInChI=1S/C43H58N4O12.C6H7N3O/c1-21-12-11-13-22(2)42(55)45-33-28(20-44-47-17-15-46(9)16-18-47)37(52)30-31(38(33)53)36(51)26(6)40-32(30)41(54)43(8,59-40)57-19-14-29(56-10)23(3)39(58-27(7)48)25(5)35(50)24(4)34(21)49;7-9-6(10)5-1-3-8-4-2-5/h11-14,19-21,23-25,29,34-35,39,49-53H,15-18H2,1-10H3,(H,45,55);1-4H,7H2,(H,9,10)/b12-11+,19-14+,22-13-,44-20+;/t21-,23+,24+,25+,29-,34-,35+,39+,43-;/m0./s1KGTSLTYUUFWZNW-PPJQWWMSSA-N[(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-[(E)-(4-methylpiperazin-1-yl)iminomethyl]-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(29),2,4,9,19,21,25,27-octaen-13-yl] acetate;pyridine-4-carbohydrazide959.46403515959.464035152881740081866909904402
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