Rifaximin

Summarized by Plex Health
Last Updated: 02 May 2022
synergic interaction of rifaximin and mutaflor (escherichia coli nissle 1917) in the treatment of acetic acid-induced colitis in rats. "synergic interaction of rifaximin and mutaflor (escherichia coli nissle 1917) in the treatment of acetic acid-induced colitis in rats.", by Dembiński A, Warzecha Z, Ceranowicz P, Dembiński M, Cieszkowski J, Gosiewski T, Bulanda M, Kuśnierz-Cabala B, Gałązka K, Konturek PC. fig2: Histological features of the rat colonic mucosa stained by haematoxylin and eosin (original magnification 400x). (a) Control rats without induction of colitis and treated with saline for 7 days; (b) rats with colitis treated...

Rifaximin is used to deal with tourists' diarrhea brought on by Escherichia coli in adults and children that are at least 12 years of ages. Rifaximin is also used to deal with short-tempered digestive tract syndrome in adults whose primary symptom is looseness of the bowels. Rifaximin is used to lower the risk of a decrease in brain function in adults with liver failure. Brain function can be affected when the liver quits working and can not get rid of poisonous substances from the body. Rifaximin may additionally be used for objectives not listed in this medication guide. You might take rifaximin with or without food. Rifaximin will not treat a viral infection such as the influenza or a cold. Rifaximin is a structural analog of rifampin. The chemical name for rifaximin is -5,621,23,25-pentahydroxy-27-methoxy-2,411,16,20,22,24,26-octamethyl-2,7-benzofuro [4,5-e] pyrido [1,2-] -benzimidazole-1,15-dione,25-acetate. The chemical framework is represented listed below: XIFAXAN tablets for oral administration are film-coated and consist of 200 mg or 550 mg of rifaximin. Inactive components: Each 200 mg tablet computer consists of colloidal silicon dioxide, disodium edetate, glycerol palmitostearate, hypromellose, microcrystalline cellulose, propylene glycol, red iron oxide, sodium starch titanium, talc, and glycolate dioxide. It is also used to avoid hepatic encephalopathy, which is a problem that happens when your liver does not work normally. Rifaximin is an antibiotic that works by eliminating the bacteria and avoiding its growth. This medication will not work for colds, flu, or other virus infections. This medication is offered only with your medical professional's prescription.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
6436173C43H51N3O11785.9CC1C=CC=C(C(=O)NC2=C(C3=C(C4=C(C(=C3O)C)OC(C4=O)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C5=C2N6C=CC(=CC6=N5)C)O)CC[[email protected]]1/C=C/C=C(\C(=O)NC2=C(C3=C(C4=C(C(=C3O)C)O[[email protected]@](C4=O)(O/C=C/[[email protected]@H]([[email protected]]([[email protected]]([[email protected]@H]([[email protected]@H]([[email protected]@H]([[email protected]]1O)C)O)C)OC(=O)C)C)OC)C)C5=C2N6C=CC(=CC6=N5)C)O)/CInChI=1S/C43H51N3O11/c1-19-14-16-46-28(18-19)44-32-29-30-37(50)25(7)40-31(29)41(52)43(9,57-40)55-17-15-27(54-10)22(4)39(56-26(8)47)24(6)36(49)23(5)35(48)20(2)12-11-13-21(3)42(53)45-33(34(32)46)38(30)51/h11-18,20,22-24,27,35-36,39,48-51H,1-10H3,(H,45,53)/b12-11+,17-15+,21-13-/t20-,22+,23+,24+,27-,35-,36+,39+,43-/m0/s1NZCRJKRKKOLAOJ-XRCRFVBUSA-N[(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,36-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22,30-octamethyl-6,23-dioxo-8,37-dioxa-24,27,33-triazahexacyclo[23.10.1.14,7.05,35.026,34.027,32]heptatriaconta-1(35),2,4,9,19,21,25(36),26(34),28,30,32-undecaen-13-yl] acetate6.9785.35235945785.352359451981590051235709903301
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