Riluzole

Summarized by Plex Health
Last Updated: 02 May 2022
riluzole-triggered gsh synthesis via activation of glutamate transporters to antagonize methylmercury-induced oxidative stress in rat cerebral cortex. "riluzole-triggered gsh synthesis via activation of glutamate transporters to antagonize methylmercury-induced oxidative stress in rat cerebral cortex.", by Deng Y, Xu ZF, Liu W, Xu B, Yang HB, Wei YG. fig4: The figure showed the immunohistochemistry assay of 8-OHdG in cerebral cortex after MeHg exposure and riluzole pretreatment. Light microphotographs were for control (a), riluzole alone (b), MeHg alone (c), and riluzole + MeHg (d)...

Riluzole is used to deal with amyotrophic lateral sclerosis, called ALS or Lou Gehrig's disease. Riluzole is not a remedy for ALS, yet it might prolong survival for patients in the very early stages of the disease or prolong the time up until a tracheostomy is needed. This medication is available only with your physician's prescription.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
5070C8H5F3N2OS234.20C1=CC2=C(C=C1OC(F)(F)F)SC(=N2)NC1=CC2=C(C=C1OC(F)(F)F)SC(=N2)NInChI=1S/C8H5F3N2OS/c9-8(10,11)14-4-1-2-5-6(3-4)15-7(12)13-5/h1-3H,(H2,12,13)FTALBRSUTCGOEG-UHFFFAOYSA-N6-(trifluoromethoxy)-1,3-benzothiazol-2-amine3.6234.00746845234.0074684576.423801711500000001
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