Rivastigmine

Summarized by Plex Health
Last Updated: 03 May 2022

Rivastigmine is used to deal with mild to moderate dementia caused by Alzheimer's or Parkinson's disease. You should not take oral rivastigmine if you have ever had extreme redness, itching, or skin irritation created by using a rivastigmine transdermal skin spot. You may swallow the liquid medication directly from the syringe or mix the medicine with a small glass of water, fruit juice, or soda. Rivastigmine is a viscous, clear, and anemic to yellow to very somewhat brown fluid that is sparingly soluble in water and very soluble in ethanol, acetonitrile, n-octanol and ethyl acetate. The distribution coefficient at 37 C in n-octanol/phosphate buffer option pH 7 is 4. 27. Rivastigmine Transdermal System is for transdermal administration. The spot is a 4-layer laminate containing the support layer, medication matrix, glue matrix and launch liner. The release lining is eliminated and thrown out prior to use. Excipients within the formulation include acrylic adhesive, acrylates copolymer, silicone adhesive. Rivastigmine will not heal or stop Alzheimer's disease or Parkinson's disease from worsening, nonetheless, rivastigmine can improve the thinking capability in some patients. In Alzheimer's disease, many chemical changes take place in the brain. ACh assists the brain to work properly. Rivastigmine slows down the failure of ACh, so it can accumulate and have a greater result. This medication is offered only with your physician's prescription.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
77991C14H22N2O2250.34CCN(C)C(=O)OC1=CC=CC(=C1)C(C)N(C)CCCN(C)C(=O)OC1=CC=CC(=C1)[[email protected]](C)N(C)CInChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1XSVMFMHYUFZWBK-NSHDSACASA-N[3-[(1S)-1-(dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate2.3250.168127949250.16812794932.826900351801100001
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