SADDAN is a rare disorder of bone growth characterized by skeletal, brain, and skin problems. All people with this problem have very short stature with especially short arms and legs. Structural problems of the brain cause seizures, profound developmental delay, and intellectual special needs. Numerous affected people have had episodes in which their breathing quits or slows for brief durations. Acanthosis nigricans, a progressive skin disorder defined by thick, dark, velvety skin, is another characteristic feature of SADDAN that develops in early stage or early childhood years.
* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions
** If you believe that content on the Plex is summarised improperly, please, contact us, and we will get rid of it quickly; please, send an email with a brief explanation.