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Sickle Cell Disease

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Last Updated: 20 September 2021

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General | Latest Info

Sickle Cell Disease

CausesGenetic
ComplicationsChronic pain , stroke , aseptic bone necrosis , gallstones , leg ulcers , priapism , pulmonary hypertension , vision problems, kidney problems
Deaths114,800 (2015)
Diagnostic methodBlood test
Frequency4.4 million (2015)
Other namesSickle cell disorder
PrognosisLife expectancy 40-60 years (developed world)
SpecialtyHematology , medical genetics
SymptomsAttacks of pain, anemia , swelling in the hands and feet , bacterial infections , stroke
TreatmentVaccination , antibiotics , high fluid intake, folic acid supplementation, pain medication , blood transfusions
Usual onset5-6 months of age

Sickle cell disease is a team of inherited red blood cell disorders that affects hemoglobin, the protein that brings oxygen via the body. People who have this form of SCD inherit a sickle cell gene from one moms and dad and from the other moms and dad a gene for an abnormal hemoglobin called C. Hemoglobin is a healthy protein that enables red cell to carry oxygen to all parts of the body. People that have this form of SCD acquire one sickle cell gene from one moms and dad and one gene for beta thalassemia, another type of anemia, from the various other moms and dad. People with HbS beta +-thalassemia tend to have a milder form of SCD.

A bone marrow or stem cell transplant is a treatment that takes healthy and balanced cells that form blood from one person-the donor-and places them into a person whose bone marrow is not functioning appropriately.

The symptoms and signs of sickle cell disease are created by the sickling of red blood cells. The quick break down of red blood cells may additionally cause yellowing of the eyes and skin, which are indicators of jaundice. Excruciating episodes can occur when sickled red blood cells, which are tight and stringent, obtain embeded tiny capillary. A specifically major issue of sickle cell disease is high blood pressure in the blood vessels that supply the lungs, which can cause cardiac arrest. Pulmonary hypertension happens in about 10 percent of grownups with sickle cell disease. Individuals have hemoglobin S-beta thalassemia disease if anomalies that create hemoglobin S and beta thalassemia occur with each other.

Typically, red blood cells are disc flexible and designed to relocate easily through the blood vessels.

The symptoms of sickle cell disease can differ from one person to another and can transform over time.

Sickle cell intrahepatic cholestasis is a uncommon yet serious type of liver damages that occurs when sickled red cells block blood vessels in the liver. People who have sickle cell disease usually have moderate to modest anemia. Extreme anemia in a newborn or youngster who has sickle cell disease may be a result of: aplastic situation.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

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03 April 2018Sickle Cell Disease | Pathophysiology, Symptoms and Treatment

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

Sickle Cell Disease (latest news)

Sickle-shaped cells include malfunctioning haemoglobin -an iron-rich protein that makes it possible for red blood cells to bring oxygen. Lots of people birthed with SCD will have had a stroke by the time they are 18 years old. Fights attacking bacteria in the blood Controls the degree of blood cells. Filters the blood and eliminates any type of broken or old red blood cells. If the spleen does not work properly-as seen in those with SCD-then it might start to get rid of healthy blood cells.

Discomfort is a constant of Beverly Chukwudozie's whole life. Chukwudozie says she meets people that are completely ignorant of sickle cell, also scared they may catch it from her.

Various difficulties that influence your bones and the way you function since red blood cells do not bring adequate oxygen. There are a lot of terrific clinical physicians trying to boost the care and study for sickle cell disease, said Chukwudozie, who calls people dealing with sickle cell warriors who require to be their own best advocates.

CULLMAN, Ala. -Kasseus Coleman, 5, was born with extreme sickle cell disease.

Azrael is our hero, Lowe claimed in the email.

While the miracle came as a blessing to the family, Lowe claimed that there would be hardships in the days to come. My child will be working as high as she can to pay their month-to-month bills, buy food and gas, traveling to and from the hospital to see her kid Kasseus and going to therapy, stated Lowe.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

Sources

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

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