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Sirius Disorder

Summarized by PlexPage
Last Updated: 02 July 2021

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General | Latest Info

Sirius Disorder

Broadcast areaOff-air
FrequencySirius 33 Dish Network 6033
SloganAdventurous music for grownups, from a diversity of styles and eras.
Programming
FormatFreeform /eclectic rock
Ownership
OwnerSirius Satellite Radio
Technical information
ClassSatellite radio station

Lithium is a 1990s grunge and Alternative rock channel airing on SIRIUS XM Radio channel 34 and Dish Network channel 6034. It debuted on SIRIUS Satellite Radio on February 14 2007, moving SIRIUS Disorder to channel 32 and later to channel 70. An Update was sent to all SIRIUS radios which corrected issues where Lithium was called '90s Alternative and Stiletto radios displayed SIRIUS logo. SIRIUS radios and website display channel as Lithium. It takes its name from Nirvana's song, Lithium. Lithium was the first all-1990s channel since I-90 signed off on November 4 2002. While the primary focus is grunge and Alternative rock, channel also plays bands from the late 1990s wave of nu Metal and Alternative Metal, such as Korn, Limp Bizkit, Orgy, Slipknot and Tool.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

What Is Psoriasis?

Psoriasis is a skin disorder that causes skin cells to multiply up to 10 times faster than normal. This makes skin build up into bumpy red patches covered with white scales. They can grow anywhere, but most appear on scalp, elbow, knees, and lower back. Psoriasis can't be passed from person to person. It does sometimes happen to members of the same family. Psoriasis usually appears in early adulthood. For most people, it affects just a few areas. In severe cases, Psoriasis can cover large parts of the body. Patches can heal and then come back throughout person's life.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

Diagnosis

CSS should be suspect in newborns with underdeveloped nails and short fifth fingers and distinctive facial features. Facial features may become more apparent as a child grows. Diagnosis is based upon thorough clinical evaluation and characteristic physical findings. However, physical features of CSS may be more variable as more individuals are diagnose. Specialized testing may be conducted to detect certain findings that may be associated with disorder. Diagnostic criteria were proposed in 2012 noting that most affected individuals have short fifth fingers with absent or underdeveloped nails, developmental and / or cognitive delays, and facial features such as wide mouth and broad nose. Give recent discovery of genetic mutations causing CSS, diagnostic criteria will likely evolve to include clinical evaluations and molecular testing. It is possible that diagnosis of CSS may be suggested before birth based upon specialized tests such as ultrasound. During fetal ultrasonography, reflected sound waves are used to generate an image of a developing fetus. Ultrasound studies may reveal characteristic findings, such as cardiac or kidney malformations and intrauterine growth retardation, which may be associated with disorder. If a disease causing mutation has been identified in the affected family member, molecular testing can be done on the fetus. This involves removal of fetal cells through chorionic villus sampling or amniocentesis. DNA extracted from fetal cells is then examined to see if mutations are present in the fetus. Molecular genetic testing is available as a diagnostic service at specialized laboratories. If indicate, further examinations and specialized imaging techniques are recommended to establish the extent of disorder. For example, MRI may be used to detect structural abnormalities, such as in the brain. During MRI, radio waves and magnetic fields are used to generate image. X-rays of hands can be performed to confirm underdevelopment or absence of end bones in five fingers. Echocardiograms, which are a type of ultrasound, can be used to generate images of the heart to detect any cardiac abnormalities that may be present. Other examinations can include developmental examinations, dietary evaluations, and eye and hearing examinations. Once diagnose, individuals with CSS should have yearly follow-up exams. This includes evaluation by a pediatrician to assess developmental progress and to determine the need for any educational or therapeutic interventions and follow-ups with other specialists to track any feeding, gastrointestinal, vision, or hearing abnormalities.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

Why it happens

While much of the talk previous to today center around changes to XMs lineup, Sirius XM has made changes to both lineups effective immediately. Essentially, it takes large majority of channels on either service and combines them, with few stations either going off air or being moved onto either service online Radio offerings. Elvis Radio-XM 18-Elvis Bridge-XM 27-Soft Classic Rock BBC Radio One-XM 29-Popular music Coffeehouse-XM 51-Adult alternative Faction-XM 52-Punk, hard Rock Radio Margaritaville-XM 55-Jimmy Buffett Jam On-XM 56-Jam band Grateful Dead Radio-XM 57 E Street Radio-XM 58 Underground Garage-XM 59-Underground Rock and Roll Shade 45-XM 66-Eminem produce station Hair Nation-XM 41-Hair band Outlaw Country-XM 12-alternative Country 21 channels are changing names, and 11 will be moving around on dial. More information on the XM lineup can be found here. 40s on 4-Sirius 4-40s music 90s on 9-Sirius 9-90s music Loft-Sirius 29-Acoustic Rock Willies Place-Sirius 64-Country enLighten-Sirius 67-Southern Gospel BB Kings Bluesville-Sirius 76-Jazz Escape-Sirius 76-Pop instrumentals Cinemagic-Sirius 81-Movie soundtracks 23 channels would change names, and 2 channels would be move. More information on the Sirius lineup can be found here. Essentially, where name is changing, it means that channel is being combined with a similar channel on another service. While this is not by any means a combination of the entire lineup, I guess Sirius XM want to keep both services separate enough that either is attractive to customers, yet similar enough that they save money on eliminating duplicate programming. My only complaint is how this was put on customers. No warning at all, only rumors. I am a regular listener of BPM XM 81, and I haven't heard them mention once about what was going on. That is just not good business for me.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

Merger with Lucy Edit

Other formats Edit

NameFormatStatusStreaming
ATN-Asian RadioSouth Asian MusicAvailable760
Carlin's Corner - XLUncensored stand-up comedy with George CarlinAvailable
Dirty Dog - XLDown Dirtiest ComedyUnavailable
Entretenimiento SiriusXMShowbizAvailable
Fox News TalkTalk radioAvailable
Jason Ellis - XLTalkAvailable
SiriusXM Comedy Showcase - XLComedy from The Comedy ClubUnavailable
Sirius XM Limited EngagementsLimited-run channels.Available
Sirius XM on DemandOn Demand Sirius XM serviceAvailable
Sirius XM Patriot PlusConservative talkU.S. only
SportsCenterSound simulcast of latest episode from ESPNAvailable
UCB Radio - XLSkits, Sketches and Underground ComedyUnavailable
Vivid Radio - XLPornography /sexual talkU.S. only
Wake Up With Jordan PeltzConservative talkU.S. only

Since 2008, Sirius XM Radio has had a similar channel lineup, with few differences based on whether individual has Sirius, XM, or SiriusXM Radio. For technical reasons, separate radios continue to be manufactured for separate services despite programming lineups having since been merge. Lynx and Edge radios are on the SiriusXM platform, Onyx and XM3pi radios are on the XM platform, and Sportster and Starmate radios are on the Sirius platform. The following is a list of channels on Sirius XM and Sirius XM Canada. There are over 150 full-time channels on Sirius XM, and over 140 of which are on Sirius XM Canada. Not include are channels that are specifically used for live sports programming, as well as former music channels that were merged with duplicate music channels after the merger.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

Preview Edit

NameFormatSatelliteInternet
Sirius XM PreviewSirius XM Promos and InformationFreeAvailable

Pop Edit

NameFormatCore artistsSatelliteInternetSiriusXMDish Network
Sirius XM Hits 1CHR/PopThe Jonas Brothers Taylor Swift Ed Sheeran Halsey The Chainsmokers Shawn Mendes Ariana Grande 5 Seconds of SummerAvailableAvailable26002
Pandora Now - xLMixed HitsCardi B Ariana Grande Post Malone Khalid Dua Lipa Bad BunnyAvailableAvailable3N/A
SoulCycle RadioUpbeat pop and rockBeyonce Drake Lady Gaga Zedd Rihanna Jay-Z Cardi B The Chainsmokers Kanye West Ariana GrandeAvailableAvailable4N/A
'50s on 5Hits from the 1950sElvis Presley Jerry Lee Lewis Brenda Lee Buddy Holly Everly Brothers Little Richard Connie Francis Ricky Nelson Fats Domino The PlattersAvailableAvailable56005
'60s on 6Hits from the 1960sThe Beatles The Beach Boys The Supremes The Four Tops Dave Clark Five Creedence Clearwater Revival The Rolling Stones Aretha Franklin Petula ClarkAvailableAvailable66006
'70s on 7Hits from the 1970sABBA Bee Gees Chicago Earth, Wind Fire Elton John KC and the Sunshine Band Paul McCartney and Wings Stevie Wonder Eagles Bachman-Turner OverdriveAvailableAvailable76007
'80s on 8Hits from the 1980sJourney Michael Jackson Def Leppard Madonna Hall Oates Duran Duran Huey Lewis and the News Prince Pat Benatar Phil CollinsAvailableAvailable86008
'90s on 9Hits from the 1990sJanet Jackson Aerosmith Madonna Ace of Base Alanis Morissette Dave Matthews Band Mariah Carey Will Smith TLC Goo Goo DollsAvailableAvailable96009
Pop2K (formerly KISS and XM Hitlist)Hits from the 2000sJustin Timberlake Nelly Eminem Matchbox Twenty Usher Rihanna Lady GagaAvailableAvailable106010
KIIS-FMCHR/PopDua Lipa Ed Sheeran Lewis Capaldi Billie Eilish Shawn Mendes The Chainsmokers Charlie Puth Selena Gomez Zedd Camila Cabello Justin BieberAvailableAvailable11N/A
PopRocks90s and 2000s Rock and Pop hitsThe Killers Coldplay Sheryl Crow Third Eye Blind Goo Goo Dolls Train No Doubt Dave Matthews Band Weezer Green DayAvailableAvailable12N/A
Pitbull's GlobalizationCurrent Rhythmic, Dance, and international HitsPitbull Dua Lipa Camilla Cabello Meduza Lizzo Tones I Galantis Netta Jax JonesAvailableAvailable136004
The Coffee HouseSinger-Songwriters , acoustic rock , folk rockJack Johnson Norah Jones George Ezra Passenger Ed Sheeran Shawn Mendes Jason Mraz David Gray Vance JoyAvailableAvailable146014
The Pulse (formerly Flight 26)Hot Adult Contemporary , 2000s Adult Contemporary and Modern Adult Pop hits from the 2000s and TodayPink Rob Thomas Andy Grammer Fitz and the Tantrums Kelly Clarkson Goo Goo Dolls OneRepublic ColdplayAvailableAvailable156015
The BlendMainstream commercial music and Classic HitsChicago Elton John Billy Joel Lionel Richie Phil Collins Hall Oates Rod StewartAvailableAvailable166016
The BridgeMellow classic rock , 70s folk rockFleetwood Mac Eagles Elton John James Taylor Billy Joel The Beatles Simon Garfunkel Jackson Browne Van Morrison Crosby, Stills, Nash YoungAvailableAvailable176032
Sirius XM Love (formerly The Heart )Love songs and Soft Adult Contemporary hitsCeline Dion Lionel Richie Mariah Carey Kenny Rogers Whitney Houston Phil Collins Barbra Streisand Barry Manilow Gloria EstefanAvailableAvailable706070
Road Trip RadioPop road trip musicAC/DC Gloria Estefan The Beach Boys The Doobie Brothers Michael Jackson Avicii Tom Petty The Rolling Stones Kenny Chesney PrinceAvailableAvailable301
The Covers ChannelEclectic covers of pop musicBoyce Avenue Florence + The Machine Vitamin String Quartet Bastille Cat Power Michael Buble Birdy Smashing Pumpkins Jack Johnson Imagine DragonsAvailableAvailable302
Venus (formerly Top 20 on 20 )Rhythmic PopBeyonce Britney Spears Christina Aguilera The Black Eyed Peas Jennifer Lopez Lady Gaga Mariah Carey Mary J. Blige Pink RihannaAvailableAvailable3036003
VelvetToday's pop vocalistsMichael Buble Cast of Glee Adele Josh Groban Susan Boyle Sam Smith Idina Menzel John Legend Adam LambertAvailableAvailable304

Table

NameFormatCore artistsSatelliteInternetSiriusXMDish Network
The JointReggaeBob Marley and the Wailers Gregory Isaacs Jimmy Cliff Burning Spear Peter Tosh Shaggy Vybz Kartel Rebelution Stick Figure Fortunate YouthAvailableAvailable426042
LL Cool J's Rock the Bells Radio - xL (replaced XM's xL The Rhyme , formerly Back Spin)1970s-1990s hip hop , golden age hip hop , 1980's "new school" hip hop , old school hip hop , hip hop classicsN.W.A Wu Tang Clan Public Enemy A Tribe Called Quest Outkast MC Lyte Kool Moe Dee The Cold Crush Brothers Stetsasonic Ultramagnetic MCsAvailableAvailable436043 (formerly 6046)
Hip-Hop Nation - xL (replaced XM's The City )Modern Hip hop hits and Uncensored Hip-hopJ. Cole Kendrick Lamar 21 Savage DaBaby Lil Wayne 2 Chainz Drake Eminem Meek Mill Schoolboy QAvailableAvailable446044
Shade 45 - xL (replaced XM's xL 66 Raw)Progressive Hip hop music and Eminem 's uncensored Hardcore hip-hopEminem Drake 50 Cent Kendrick Lamar Dr. Dre Kanye West Travis Scott Action Bronson Wiz Khalifa Big Sean Tech N9ne Schoolboy QAvailableAvailable456045
The Heat (replaced XM's The Eye formerly Hot Jamz )Rhythmic Contemporary , Urban Pop , Urban contemporary and Hip-hop and RB hitsRihanna Drake Miguel Beyonce Ty Dolla $ign The Weeknd SZA Chris Brown LogicAvailableAvailable466046 (formerly 6047)
SiriusXM FLY - xL1990's-2000's Hip hop and RB hitsSnoop Dogg Boyz II Men Ludacris Alicia Keys Jodeci Dr. Dre Lauryn Hill / Fugees Tupac Shakur Missy Elliot The Notorious B.I.G.AvailableAvailable476047
Heart Soul (replaced XM's Suite 62)Urban Adult Contemporary and Adult RB hits of the 1980s to PresentJohn Legend Maxwell Prince Joe Charlie Wilson Jill Scott Kem Tyrese Gibson Toni Braxton Brian McKnightAvailableAvailable486048
Soul Town (formerly Soul Revue) (replaced XM's Soul Street )1960s, 1970s and 1980s Classic Soul and MotownAretha Franklin Marvin Gaye The Temptations Diana Ross Stevie Wonder The Supremes James Brown Smokey Robinson Gladys Knight The SpinnersAvailableAvailable496049
The Groove1960s-1980s Old school RB , funk , and discoMichael Jackson Luther Vandross Marvin Gaye Earth, Wind Fire The Gap Band Commodores Prince Stevie Wonder Chaka KhanAvailableAvailable506050
SiriusXM SilkSmooth RB love songsLuther Vandross Whitney Houston Marvin Gaye Sade Maxwell The Isley Brothers Stevie Wonder Prince Anita Baker Patti LaBelleAvailableAvailable330

Dance / Electronic Edit

NameFormatCore artisisSatelliteInternetSiriusXMDish Network
BPMCurrent-based Dance hitsThe Chainsmokers Calvin Harris Tiesto Armin Van Buuren Kaskade Marshmello Eric Prydz Martin Garrix Morgan PageAvailableAvailable516051
Diplo's Revolution (formerly Electric Area and The Move )Progressive trance , progressive house , various EDM and house music artistsDiplo DJ Snake Chris Lake AlunaGeorge Major Lazer MK Skrillex Dillon FrancisAvailableAvailable526052
Sirius XM ChillChill out music , downtempo , ambient electronica / ambient house , trip hop , acid jazz , nu jazz , indietronica , chillwaveODESZA Nora En Pure Autograf Kaskade Moby Kygo Lost Frequencies Robin SchulzAvailableAvailable536053
Studio 54 Radio (formerly BBC Radio 1 simulcast, Chrome (XM) , and The Strobe )Disco , freestyle musicDonna Summer Silver Convention Salsoul Orchestra Chic Lipps, Inc. Sister Sledge France Joli Change Debbie Deb AlishaAvailableAvailable546054 (formerly 6015)
UtopiaDance hits from the 1990s and 2000sCascada Daft Punk Deborah Cox Fatboy Slim Janet Jackson Kylie Minogue Lady Gaga Madonna RobynAvailableAvailable3416055

Country Edit

NameFormatCore artistsSatelliteInternetSiriusXMDish Network
The Garth ChannelGarth Brooks' music channelGarth BrooksU.S. onlyAvailable556055
The Highway (formerly Highway 16 )Modern Country Music and New Country musicEric Church Blake Shelton Miranda Lambert Luke Bryan Jason Aldean Florida Georgia Line Thomas RhettAvailableAvailable566056
No Shoes Radio ( Kenny Chesney's music channel)Chesney's music plus Jimmy Buffett , easy listening , easy country, Caribbean , relaxingAvailableAvailable576057
Prime Country (formerly U.S. Country)Classic Country from the 1980s and the 1990sGarth Brooks George Strait Reba McEntire Alabama Alan Jackson Randy Travis The Judds Clint Black Trisha Yearwood Brooks DunnAvailableAvailable586058
Willie's Roadhouse (formerly The Roadhouse and Willie's Place )Classic country and Willie Nelson 's Texas Traditional Country from the 1960s and the 1970sWillie Nelson Merle Haggard George Jones Conway Twitty Johnny Cash Charley Pride Kenny Rogers Loretta Lynn Ronnie Milsap Dolly Parton Waylon Jennings Patsy ClineAvailableAvailable596059
Outlaw Country (formerly X Country )Outlaw country and Country music from the 1980s, 1990s and early 2000sJohnny Cash Waylon Jennings Willie Nelson Merle Haggard Dwight Yoakam Steve Earle Emmylou Harris Lucinda Williams Jamey Johnson Jason Isbell Sturgill SimpsonAvailableAvailable606060
Y2KountryCountry music from the late 1990s, 2000s, and 2010s (1997-2019)Toby Keith Kenny Chesney Tim McGraw Brad Paisley Carrie Underwood George Strait Rascal Flatts Keith Urban Brooks Dunn Taylor Swift The Chicks Martina McBrideAvailableAvailable616061
Bluegrass JunctionBluegrassBill Monroe Del McCoury Flatt Scruggs Doyle Lawson Ricky Skaggs Rhonda Vincent The Grascals Jimmy Martin Osborne Brothers Chris JonesAvailableAvailable626062
Dwight Yoakam the Bakersfield BeatMusic from Dwight YoakamDwight Yoakam Buck Owens Merle Haggard Wynn Stewart Tommy Collins The Byrds The Flying Burrito Brothers Ricky Nelson Freddie Hart Lucinda WilliamsAvailableAvailable349
Red, White BoozeCountry bar songsToby Keith Kenny Chesney Luke Bryan Zac Brown Band Jason Aldean Kid Rock Aerosmith Lynyrd SkynyrdAvailableAvailable350

Christian Edit

NameFormatCore artistsSatelliteInternetSiriusXMDish Network
The MessageContemporary ChristianChris Tomlin MercyMe Jeremy Camp Francesca Battistelli Casting Crowns TobyMac For King Country Mandisa Steven Curtis ChapmanAvailableAvailable636063
Kirk Franklin's Praise (formerly Spirit )Gospel , created by Kirk FranklinKirk Franklin Tamela Mann Donnie McClurkin Le'Andria Johnson Fred Hammond Tasha Cobbs Leonard Tina Campbell Shirley Caesar Donald Lawrence Tye TribbettAvailableAvailable646064
enLightenSouthern GospelBill Gaither Booth Brothers Gold City Brian Free Assurance Karen Peck and New River Greater Vision Whisnants The Talleys The Perrys Ernie Haase Signature SoundAvailableAvailable656065

Jazz / Standards Edit

NameFormatCore artistsSatelliteInternetSiriusXMDish Network
WatercolorsSmooth JazzDave Koz Brian Culbertson Boney James Maysa Leak David Benoit George Benson Al Jarreau Peter White Sade Paul HardcastleAvailableAvailable666066
Real JazzTraditional JazzMiles Davis John Coltrane Wynton Marsalis Duke Ellington Dizzy Gillespie Christian McBride McCoy Tyner Art Blakey Charlie Parker Thelonious MonkAvailableAvailable676067
SpaNew Age / Ambient MusicPeter Kater Steven Halpern Brian Eno Paul Winter Tangerine Dream Mark Isham Will Ackerman David Arkenstone KitaroAvailableAvailable686068
EscapeBeautiful musicPercy Faith Bert Kaempfert John Fox James Last Henry Mancini Richard Clayderman Caravelli Tony MottolaAvailableAvailable696069
Siriusly Sinatra (formerly High Standards)Standards , Jazz , and SwingFrank Sinatra Tony Bennett Ella Fitzgerald Peggy Lee Dean Martin Nat King Cole Michael Buble Rosemary Clooney Bobby Darin Sammy Davis Jr.AvailableAvailable716071
On BroadwayShowtunesJulie Andrews Barbra Streisand Liza Minnelli Nathan Lane Bernadette Peters Kristin Chenoweth Tommy Tune Angela Lansbury Patti LuPone Lin-Manuel MirandaAvailableAvailable726072
'40s Junction (formerly 40s on 4 )Big Band, Swing and Pop Hits from the 1940sGlenn Miller Artie Shaw Benny Goodman The Dorsey Brothers Bing Crosby Duke Ellington Count Basie Les Brown Doris DayAvailableAvailable736073
B.B. King's BluesvilleBluesB.B. King Stevie Ray Vaughan Muddy Waters Buddy Guy Eric Clapton Etta James Robert Cray Joe Bonamassa John Lee Hooker Johnny WinterAvailableAvailable746074

Classical Edit

NameFormatCore artistsSatelliteInternetSiriusXM
Met Opera RadioOperaRenee Fleming Anna Netrebko Placido Domingo Luciano Pavarotti Joan Sutherland Juan Diego Florez Natalie Dessay Bryn Terfel Jonas KaufmannAvailableAvailable75
Symphony HallClassical musicJohn Adams Ludwig van Beethoven Johann Sebastian Bach Joshua Bell Johannes Brahms Antonin Dvorak Gustavo Dudamel Joseph Haydn Jennifer Higdon Yuja WangAvailableAvailable76

Family Edit

NameFormatSatelliteInternetSiriusXM
Kidz Bop RadioToday's pop songs covered by the Kidz Bop kidsAvailableAvailable77
Kids Place LiveChildren'sAvailableAvailable78
Radio DisneyRadio Disney music and hitsAvailableAvailable79

Sports Edit

NameFormatSatelliteInternetSiriusXM
ESPN RadioSports TalkAvailableAvailable80
ESPN XtraSports NewsAvailableAvailable81
Mad Dog Sports RadioSports Talk created and hosted by Chris "Mad Dog" RussoAvailableAvailable82
Fox Sports on Sirius XMSports TalkAvailableAvailable83
ESPNU RadioSports TalkAvailableAvailable84
Barstool Radio - XLSatirical Sports and Uncensored Men's TalkAvailableAvailable85
Sirius XM NBA RadioSports TalkAvailableAvailable86
Sirius XM Fantasy Sports RadioFantasy Sports TalkAvailableAvailable87
Sirius XM NFL RadioSports TalkAvailableAvailable88
MLB Network RadioMajor League Baseball ChannelAvailableAvailable89
Sirius XM NASCAR RadioNASCAR Racing and TalkAvailableAvailable90
Sirius XM NHL Network RadioNational Hockey League talk play-by-playAvailableAvailable91
Sirius XM PGA Tour RadioLive PGA Tour golf and talkAvailableAvailable92
Sirius XM Fight NationCombat sportsAvailableAvailable156
Sirius XM FCSoccer Talk Play-By-PlayU.S. onlyAvailable157
Vegas Stats Information NetworkSports betting talkU.S. onlyAvailable204
IndyCar RadioNTT INDYCAR Series RacingAvailableAvailable205
CBS Sports RadioSports talkAvailableAvailable206
Dan Patrick RadioSports talkAvailableAvailable211
ESPN PodcastsBest of ESPN and 30 for 30 PodcastAvailableAvailable370

Comedy Edit

NameFormatSatelliteInternetSiriusXM
Netflix is a Joke Radio - xlUncensored Netflix comedy specialsAvailableAvailable93
SiriusXM Comedy Greats - xLUncensored comedy featuring the Greatest Comedians of All-Time, Jay Thomas , Craig FergusonAvailableAvailable94
Comedy Central Radio - xLUncensored comedy from Comedy CentralAvailableAvailable95
Kevin Hart's Laugh Out Loud Radio - xLKevin Hart 's comedy and showsAvailableAvailable96
Jeff Larry's Comedy Roundup - xL (formerly Blue Collar Radio )Uncensored Comedy with Larry the Cable Guy and Jeff FoxworthyAvailableAvailable97
Laugh USAFamily ComedyAvailableAvailable98
Raw Dog Comedy - xLStand-up comedy , Uncensored comedy and BenningtonAvailableAvailable99

Entertainment Edit

NameFormatSatelliteInternetSiriusXM
Howard 100 and Howard 101 - XLHoward Stern 's uncensored channels of The Howard Stern Show and The World of Howard SternAvailableAvailable100-101
Radio Andy - XLAndy Cohen 's radio station for Uncensored talkAvailableAvailable102
Faction Talk - XLUncensored Talk with Jim Norton Sam Roberts , The Jason Ellis ShowU.S. onlyU.S. only103
VolumeMusic TalkAvailableAvailable106
Today Show Radio 108Live TV Show with Jessica Ettinger 's Behind the Scenes interviews NBC TodayAvailableUnavailable108
Sirius XM Stars - XLWomen's Uncensored Talk and EntertainmentAvailableAvailable109
Doctor RadioHealth and medical informationAvailableAvailable110
TriumphAdvice, enlightenment, and inspiration from Dave Ramsey , Glenn Beck , Nancy Grace , etc.AvailableAvailable111
Business RadioFinancial news, operated by the Wharton SchoolAvailableAvailable132
Road Dog TruckingTrucking talkAvailableAvailable146
Radio ClassicsOld Time RadioAvailableAvailable148

News/Public radio/Politics/Issues Edit

NameFormatSatelliteInternetSiriusXM
CNBCFinancial news (TV simulcast)AvailableAvailable112
Fox BusinessFinancial news (TV simulcast)AvailableAvailable113
Fox News ChannelNews (TV simulcast)AvailableAvailable114
Fox News Headlines 24/7Headlines from Fox NewsAvailableAvailable115
CNNNews (TV simulcast)AvailableAvailable116
HLNNews (TV simulcast)AvailableAvailable117
MSNBCNews (TV simulcast)AvailableAvailable118
Bloomberg RadioSimulcast of WBBR in New York CityAvailableAvailable119
BBC World Service (English North America feed)NewsAvailableAvailable120
NPR NowNPR programs arranged specifically for SIRIUSAvailableAvailable122
Public Radio ExchangePublic radioAvailableAvailable123
P.O.T.U.S.Political talkAvailableAvailable124
SiriusXM PatriotConservative TalkAvailableAvailable125
SiriusXM Urban ViewAfrican-American talkAvailableAvailable126
SiriusXM ProgressLiberal TalkU.S. onlyAvailable127
Rural RadioAgricultural news western lifestyleAvailableAvailable147
C-SPAN RadioU.S. Government Hearings and Public AffairsAvailableAvailable455
CNN InternationalNews from around the worldAvailableAvailable454

Religion Edit

NameFormatSatelliteInternetSiriusXM
Joel Osteen RadioPositive Inspiration For LifeAvailableAvailable128
The Catholic ChannelTalk For Saints and SinnersAvailableAvailable129
EWTN Global Catholic NetworkSolid Catholic TalkAvailableAvailable130
FamilyTalkChristian TalkAvailableAvailable131
The Billy Graham ChannelMessages from Billy GrahamAvailableAvailable460

Traffic/weather Edit

NameFormatSatelliteInternetSiriusXM
New YorkTraffic and weatherAvailableUnavailable133
Boston / Philadelphia / Washington D.CTraffic and weatherAvailableUnavailable134
Chicago / Detroit / Dallas-Fort WorthTraffic and weatherAvailableUnavailable135
Los AngelesTraffic and weatherAvailableUnavailable136

More Edit

NameFormatSatelliteInternetSiriusXM
H.U.R. VoicesHoward University College Radio/TalkAvailableAvailable141
HBCUHoward University HBCUs College Radio/TalkAvailableAvailable142
BYU RadioBrigham Young University College Radio/TalkAvailableAvailable143
Korea TodayKorean music, news, entertainmentAvailableAvailable144
Slam RadioSports and entertainment talkAvailableAvailable145

Holiday Edit

NameFormatSatelliteInternet
Sirius XM HollyContemporary Christmas musicHoliday onlyHoliday only
Holiday TraditionsTraditional Christmas songsHoliday onlyHoliday only
Hallmark Channel RadioChristmas songs and commentaryHoliday onlyHoliday only
Holiday PopsClassical Christmas performancesHoliday onlyHoliday only
Country ChristmasCountry Christmas musicHoliday onlyHoliday only
NavidadSpanish Christmas musicUnavilableHoliday only
Holiday SoulRB Christmas musicHoliday onlyHoliday only
Radio HanukkahHanukkah music and programmingUnavailableHoliday only
Acoustic ChristmasAcoustic musicHoliday onlyHoliday only
Christmas SpiritContemporary Christian Christmas musicHoliday onlyHoliday only
'70s-'80s HolidaysChristmas music from the 1970s and 1980sUnavailableHoliday only
Rockin' XmasClassic Christmas hits and related programmingUnavailableHoliday only
Holiday Chill-OutDowntempo electronic musicUnavailableHoliday only
Jazz HolidaysContemporary and classic jazz Christmas musicUnavailableHoliday only
New Year's NationMusic from different genres for New Year's DayUnavailableHoliday only

Latin (in Spanish) , French, Canadian, and international Edit

NameFormatCore artistsSatelliteInternetSiriusXM
American Latino RadioTalk show radioAvailableCanada only154
Caliente (in Spanish)Tropical / Latin popRomeo Santos Prince Royce Marc Anthony J Balvin Alex Matos Victor Manuelle Eddy Herrera Daddy Yankee Carlos Vives Los Hermanos RosarioAvailableAvailable158
Canada 360Canadian News WeatherAvailableAvailable
Canada TalksCanadian current affairs talkAvailableAvailable167
Canadian Indigenous Peoples' RadioCanadian indigenous musicCanadaCanada165
CBC Radio 3Canadian Indie MusicAvailableAvailable162
CBC Radio OneCanadian news and information (special national feed)AvailableAvailable169
CBC Music CountryNew Canadian CountryBrett Kissel Zac Brown Dean Brody Lindi Ortega Dallas Smith Florida Georgia Line Eric ChurchAvailableAvailable171
CNN en EspanolNewsAvailableAvailable795
Cristina RadioAdvice and Current AffairsAvailableAvailable
En VivoContemporary English Spanish HitsRicky Martin Pitbull Shakira Thalia Mana Laura PausiniAvailableAvailable152
ESPN Deportes RadioSportsU.S. onlyU.S. only
Iceberg RadioCanadian Adult AlternativeAvailableAvailable758
Ici Musique ChansonsFrench Variety MusicYann Perreau Anik Jean Les Dales Hawerchuk Damien SaezAvailableAvailable163
Ici Musique FrancoCountryFrancophone Canadian Country-FolkKarim Ouellet Louis-Jean Cormier Lisa Leblanc CanaillesAvailableAvailable166
Ici Radio-Canada PremiereRadio Canada News Information (simulcast of CBF-FM Montreal )AvailableAvailable170
Influence FrancoIndie Pop AlternativeKarim Ouellet Louis-Jean Cormier Lisa Leblanc CanaillesAvailableAvailable174
Just for Laughs Radio - XLUncensored Canadian comedyAvailableAvailable168
La Politica TalkLive Hispanic talkAvailableAvailable153
MLB en EspanolSportsAvailableUnavailable159
Multicultural RadioThe Cultures of CanadaAvailableAvailable
North AmericanaAmericana musicTom Petty Blue Rodeo JJ Shiplett Ray LamontagneAvailableAvailable359
Radio Formula MexicoNewsAvailableAvailable
SiriusXM ScoreboardFinal Sports Scores and Info (Canadian)AvailableAvailable172
The VergeCanadian New Emerging Indie/AlternativeArcade Fire City and Colour Hey Rosetta Mother Mother Stars Hollerado Metric Yukon Blonde Tegan and Sara Death from AboveAvailableAvailable173
* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

Causes

CSS is thus far known to be caused by mutations in one of the following seven genes: ARID1A, ARID1B, ARID2, SMARCA4, SMARCB1, SMARCE1 and SOX11. Genes provide instructions for creating proteins that play a critical role in many functions of the body. ARID-and SMARC-genes linked to CSS provide instructions to make several different protein complexes that are know as BRG-1 associated factor complex in humans. SOX11 is involved with transcriptional regulation of the BAF complex. These protein complexes regulate gene activity by altering how tightly regions of DNA are package, which can affect gene expression. Subsequently, BAF complex is involved in a variety of processes including cell growth, division, and differentiation and replication and repairing of DNA. It is still unclear how mutations affect the BAF complex, but researchers believe mutations alter DNA packaging, which can disrupt gene activity and cellular processes and lead to symptoms of CSS. CSS appears to be inherited as autosomal dominant condition. Genetic diseases are determined by a combination of genes for particular traits that are on chromosomes received from father and mother. Dominant genetic disorders occur when only a single copy of an abnormal gene is necessary to cause a particular disease. Abnormal genes can be inherited from either parent or can be the result of new mutation in the affected individual. The risk of passing abnormal gene from affected parent to offspring is 50 % for each pregnancy. The risk is the same for males and females. With CSS, most mutations appear to be the result of new mutations that occur during early development in embryo rather than inherit. In some dominant disorders, including CSS, disease expressions may be variable. If individuals inherit mutated genes for disease, characteristics that are expressed may vary greatly and range in severity from case to case. Other researchers indicate that CSS may be inherited as an autosomal recessive trait. In recessive disorders, conditions do not appear unless the person inherits the same defective gene for the same trait from each parent. If an individual receives one normal gene and one abnormal gene, person will be carrier of disease but usually will not show symptoms. The risk for two career parents to both passing defective gene and having affected child is 25 % with each pregnancy. The risk of having a child who is a carrier is 50 % with each pregnancy. The chance for a child to receive normal genes from each parent for that particular trait is 25 %. The risk is the same for males and females. All individuals carry 4-5 abnormal genes. Parents who are related by blood have a higher chance than unrelated parents of both carrying the same abnormal gene, which increases the risk of having children with recessive genetic disorder. Parents of some individuals with CSS have been closely related by blood. Not all affected individuals have mutations in ARID1A, ARID1B, SMARCA4, SMARCB1, SMARCE1, or SOX11 genes.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

Related Disorders

Symptoms of following disorders may be similar to those of Coffin-Siris syndrome. Comparisons may be useful for differential diagnosis: mosaic trisomy 9 is a rare chromosomal disorder in which there are three copies of chromosome number 9 rather than two in some cells of the body. Term mosaic indicate that some cells contain extra chromosome 9, while others have normal chromosomal pair. Associate symptoms and findings may vary greatly in range and severity, depending on the percentage of cells with extra chromosome. However, common features include growth deficiency before birth; mental retardation; structural malformations of the heart that are present at birth; and / or distinctive abnormalities of the skull and facial region, such as sloping forehead, bulbous nose, short eyelid folds, deeply set eyes, and / or low-set, malformed ears. Syndromes may also be characterized by musculoskeletal, genital, kidney, and / or additional physical abnormalities. Mosaic trisomy 9 may be caused by errors during division of parents ' reproductive cells or during division of body tissue cells early in the development of embryo. Cornelia de Lange syndrome is a rare genetic disorder that is apparent at birth. Associate symptoms and findings typically include delays in physical development before and after birth; characteristic craniofacial abnormalities, resulting in distinctive facial appearance; malformations of hands and arms; and mild to severe mental retardation. Many infants and children with the disorder have an unusually small, short head; abnormally long vertical groove between upper lip and nose; depressed nasal bridge; upturned nostrils; and protruding upper jaw. Additional, characteristic facial abnormalities may include thin, downturned lips; low-set ears; arch, well-define eyebrows that grow together across the base of the nose; unusually low hairline on the forehead and back of the neck; and abnormally curly, long eyelashes. Affected individuals may also have distinctive malformations of limbs, such as unusually small hands and feet, inward deviation of fifth fingers, or webbing of certain toes. Less commonly, there may be absence of forearms, hands, and fingers. Infants with Cornelia de Lange syndrome may also have feeding and breathing difficulties; increased susceptibility to respiratory infections; low-pitch growling cry; heart defect; delayed skeletal maturation; hearing loss; or other physical abnormalities. The range and severity of associated symptoms and findings may be extremely variable from case to case. Cornelia de Lange syndrome can be inherited as autosomal dominant condition or X-link condition. Genes that have been found to be associated with Cornelia de Lange syndrome are NIPBL, located on chromosome 5 and SMC1A gene on the X chromosome. Milder forms of Cornelia de Lange have been attributed to mutations in SMC3 and RAD21 genes. Most affected individuals have abnormal genes as result of new gene mutation and do not have affected parent. Other genes may be found to be associated with Cornelia de Lange syndrome in the future.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

Standard Therapies

Enrollment in the GEN501 Study commences on March 27 2008, and in the SIRIUS Study on September 30 2013. Data was previously reported from the cutoff date of January 9 2015. 11 12 At the cutoff date of December 31 2015, total of 148 patients who received daratumumab 16 mg / kg in GEN501 part 2 and SIRIUS studies were included in the combined analysis. The median duration of follow-up was 20. 7 months on the basis of Kaplan-Meier analysis. Baseline characteristics and refractory status for patients within individual studies and the combined data set are summarized in Table 1. Overall, patients were heavily pretreated, with a median of 5 prior therapies; 76. 4 % of Patients receive > 3 prior lines of Therapy. Many patients were double refractory to both PI and IMiD, 39. 2 % of patients were refractory to carfilzomib, and 55. 4 % of patients were refractory to pomalidomide. 2 Study populations were well balance. Higher percentages of patients previously treated with carfilzomib and pomalidomide in SIRIUS Study vs GEN501 Study are indicative of broader availability of these agents. Fewer median lines of prior Therapy in GEN501 Study compared with SIRIUS Study reflect inclusion criteria for these studies. The median treatment duration was 3. 4 months, and the median number of infusions was 12. The Majority of Patients discontinue from Study as result of PD; only 6 Patients in the combined data set discontinue from Study as result of AEs. Three deaths were recorded as being the result of AEs. These deaths consist of 1 case each of viral H1N1 infection, pneumonia, and aspiration pneumonia, and they were determined to be not related to Study treatment. In the combined data set, 59 and 28 of 148 patients treated with daratumumab 16 mg / kg demonstrated 50 % and 90 % reductions in paraprotein from baseline, respectively. Median time to Response in Patients with PR or better was 0. 95 months. The ORR for the combined data set was 31. 1 %. Responses include 3 Patients with sCR, 4 with CR, 13 with VGPR, and 26 with PR. The Clinical benefit rate was 37. 2 %, and 83. 1 % of patients achieve SD or better. The Median duration of Response was 7. 6 months. Responses deepened with continued daratumumab treatment in 14 patients across 2 studies. Of 10 patients with initial PR, 7 go on to achieve VGPR with further treatment. In addition, 3 patients with initial PR achieved deeper responses of CR and sCR. Responses in 4 Patients with initial VGPR continue to deepen to CR and sCR. Timing of first and best responses are shown in supplemental Figure 2. Within individual studies, ORR was 35. 7 % in GEN501 Study parts 2 and 29. 2 % in SIRIUS Study.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

Sources

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

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