GENOTROPIN lyophilized powder includes somatropin, which is a polypeptide hormonal agent of recombinant DNA beginning. The amino acid series of the item corresponds that of human growth hormone of pituitary beginning. GENOTROPIN is manufactured in a pressure of Escherichia coli that has been customized by the enhancement of the genetics for human growth hormone. GENOTROPIN is a sterilized white lyophilized powder meant for subcutaneous shot. GENOTROPIN 5 mg is dispensed in a two-chamber cartridge. The front chamber contains recombinant somatropin 5. 8 mg, glycine 2. 2 mg, mannitol 1. 8 mg, sodium dihydrogen phosphate anhydrous 0. 32 mg, and disodium phosphate anhydrous 0. 31 mg; the back chamber contains 0. 3% m-Cresol and mannitol 45 mg in 1. 14 mL water for shot. The GENOTROPIN 5 mg two-chambered cartridge has 5. 8 mg of somatropin. The cartridge includes overfill to permit for shipment of 1ml having the specified quantity of GENOTROPIN, 5 mg. GENOTROPIN 12 mg is dispensed in a two-chamber cartridge. The GENOTROPIN 12 mg two-chambered cartridge includes 13. 8 mg of somatropin. The cartridge contains overfill to permit for shipment of 1ml consisting of the stated quantity of GENOTROPIN, 12 mg. GENOTROPIN MINIQUICK is given as a single-use syringe device including a two-chamber cartridge. GENOTROPIN MINIQUICK is available as specific doses of 0. 2 mg to 2. 0 mg in 0. 2 mg increments. The reconstituted GENOTROPIN MINIQUICK two-chamber cartridge includes overfill to enable distribution of 0. 25 ml containing the specified amount of GENOTROPIN. The reconstituted recombinant somatropin solution has an osmolality of roughly 300 mOsm/kg, and a pH of roughly 6. 7.
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