Sorafenib

Summarized by Plex Health
Last Updated: 02 May 2022
ubenimex attenuates acquired sorafenib resistance in renal cell carcinoma by inhibiting akt signaling in a lipophagy associated mechanism "ubenimex attenuates acquired sorafenib resistance in renal cell carcinoma by inhibiting akt signaling in a lipophagy associated mechanism", by . F9: Storage of lipid droplets (LDs) was higher after treatment with sorafenib (A, B)In sorafenib resistant cells, treatment with sorafenib did not overtly change LD levels (C, D). Data represent three independent experiments. *P <...

Sorafenib is used to deal with liver cancer, thyroid cancer, or kidney cancer. You need to not use sorafenib if you have squamous cell lung cancer and you are being treated with carboplatin and paclitaxel. Sorafenib can cause heart problems. Sorafenib can cause or damage a coming child abnormality if the papa or the mommy is making use of sorafenib. Take sorafenib on an empty stomach, a minimum of 1 hr before or 2 hours after consuming. Sorafenib tosylate has the chemical name 4- [4-phenoxy] -Nmethylpyridine-2carboxamide, tosylate. The molecular formula of sorafenib tosylate is C21H16ClF3N4O3C7H8O3S and the molecular weight of sorafenib tosylate is 637. 03 g/mole. Sorafenib tosylate is practically insoluble in aqueous media, slightly soluble in ethanol and soluble in PEG 400. Sorafenib tablets, USP for oral use are provided as film-coated tablets having 200 mg sorafenib equal to 274 mg sorafenib tosylate, USP and the complying with non-active active ingredients: carboxymethylcellulose calcium, croscarmellose sodium, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, red iron oxide, sodium lauryl sulfate and titanium dioxide. Sorafenib is an antineoplastic agent. It disrupts the growth of cancer cells, which are at some point destroyed by the body. This medicine is readily available only with your doctor's prescription.

* Please keep in mind that all text is summarized by machine, we do not bear any responsibility, and you should always check original source before taking any actions

** If you believe that content on the Plex is summarised improperly, please, contact us, and we will get rid of it quickly; please, send an email with a brief explanation.

PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
216239C21H16ClF3N4O3464.8CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)FCNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)FInChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)MLDQJTXFUGDVEO-UHFFFAOYSA-N4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide4.1464.0863026464.086302692.464603753200000001
*** If you want us to remove all links leading to your domain from Plex.page and never use your website as a source of the "Online Knowledge", please contact us using a corporate email and we will remove everything in 10 business days.

logo

Plex Page is a Biology & Health Sciences "Online Knowledge Base," where a machine summarizes all the summaries.