Spironolactone And Hydrochlorothiazide
Summarized by Plex Health
Last Updated: 02 May 2022
Each tablet computer of spironolactone and hydrochlorothiazide has 25 mg of spironolactone, USP and 25 mg of hydrochlorothiazide, USP. Hydrochlorothiazide, an antihypertensive and diuretic, is 6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide and has the following structural formula, molecular formula and molecular weight: C7H8ClN3O4S2 M. W. = 297. 74 Hydrochlorothiazide is slightly soluble in water and freely soluble in sodium hydroxide remedy. Each tablet for oral administration includes 25 mg of spironolactone and 25 mg of hydrochlorothiazide and the adhering to inactive ingredients: colloidal silicon dioxide, corn starch, D&C Yellow No. 10 Aluminum Lake, FD&C Yellow No.
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Sources:
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0c8c973f-13a2-4883-8316-4006398e2...
PubChem - CovalentUnitCount
(Table source)| CID | MolecularFormula | MolecularWeight | CanonicalSMILES | IsomericSMILES | InChI | InChIKey | IUPACName | XLogP | ExactMass | MonoisotopicMass | TPSA | Complexity | Charge | HBondDonorCount | HBondAcceptorCount | RotatableBondCount | HeavyAtomCount | IsotopeAtomCount | AtomStereoCount | DefinedAtomStereoCount | UndefinedAtomStereoCount | BondStereoCount | DefinedBondStereoCount | UndefinedBondStereoCount | CovalentUnitCount |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 24847844 | C31H40ClN3O8S3 | 714.3 | CC(=O)SC1CC2=CC(=O)CCC2(C3C1C4CCC5(C4(CC3)C)CCC(=O)O5)C.C1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl | CC(=O)S[[email protected]@H]1CC2=CC(=O)CC[[email protected]@]2([[email protected]@H]3[[email protected]@H]1[[email protected]@H]4CC[[email protected]]5([[email protected]]4(CC3)C)CCC(=O)O5)C.C1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl | InChI=1S/C24H32O4S.C7H8ClN3O4S2/c1-14(25)29-19-13-15-12-16(26)4-8-22(15,2)17-5-9-23(3)18(21(17)19)6-10-24(23)11-7-20(27)28-24;8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h12,17-19,21H,4-11,13H2,1-3H3;1-2,10-11H,3H2,(H2,9,12,13)/t17-,18-,19+,21+,22-,23-,24+;/m0./s1 | RFNRSUBWOXSCLB-FXFKJASFSA-N | 6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide;S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxospiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,2'-oxolane]-7-yl] ethanethioate | 713.1666065 | 713.1666065 | 221 | 1310 | 0 | 3 | 12 | 3 | 46 | 0 | 7 | 7 | 0 | 0 | 0 | 0 | 2 |
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