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Stage 4 Prostate Cancer

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Last Updated: 18 January 2022

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General | Latest Info

Prostate Cancer is one of most common types of cancer that develop in men and is second leading cause of cancer deaths in American men, behind lung cancer and just ahead of colorectal cancer. Prognosis For Prostate Cancer, As With Any Cancer, Depends On How Advanced Cancer Has Become, According To Established Stage Designations. Prostate gland is walnut - size gland present only in men, found in pelvis below bladder. Prostate gland wraps around urethra and lies in front of rectum. Prostate glands secrete part of liquid portion of semen, or seminal fluid, which carries sperm made by testes. Fluid is essential to reproduction. Term Stage Cancer Is Meant To Describe Obvious Extent Of Cancer In Body At Time That Cancer Is First Diagnose. Clinical staging of Prostate Cancer is based on pathology results, physical examination, PSA, and, if radiologic studies. Stage of Cancer helps doctors understand extent of cancer and plan Cancer Treatment. Knowing overall results of different treatments for similarly stag prostate cancers can help doctors and patients make important decisions choices of treatment to recommend or to accept. Prostate Cancer comprises nearly always adenocarcinoma cells - cells arise from glandular tissue. Cancer cells are named according to organ in which they originate, no matter where in body we find such cells. If Prostate Cancer cells spread from to bones, it is labelled Prostate Cancer metastatic to bones, not bone Cancer. Metastasis is process of cancer spread through blood or lymphatic system to other organs / areas throughout body. In late stages of disease, Prostate Cancer more commonly metastasizes to lymph nodes in pelvis and to bones. Cancer staging is first described using what is called TNM system. T refers to of size or extent of primary, or original, tumor. N describes presence or absence of, and extent of spread of cancer to lymph nodes that may be nearby or further from original tumor. M describes presence or absence of metastases - usually distant areas elsewhere in body other than regional lymph nodes to which cancer has spread. Cancers with specific TNM characteristics are then grouped into stages, and stages are then assigned Roman numerals with numerals used in increasing order as extent of cancer being stag increases or cancer prognosis worsens. Prognosis is finally reflected by considering Patient's PSA Score at presentation as well as their Gleason Score in assigning final stage designation. American Joint Commission On Cancer System For Prostate Cancer Staging Is As Follow: T Designations Refer To Characteristics Of Prostate Cancer Primary Tumor. T1 Prostate cancers cannot be seen on imaging or felt on examination.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

Risk factors

Wide international variation in incidence rates 1 2 and increases in Prostate Cancer incidence and mortality rates in migrants from countries with low rates to those countries with high rates 3 - 5 demonstrate importance of modifiable etiologic factors for this cancer. However, evidence for any specific factor generally not been very consistent. Heterogeneous Nature Of Prostate Cancers, Which Range From Relatively Innocuous To Highly Aggressive In Behavior, May Contribute To Inconsistent Results. Because they may act on different biologic pathways, risk factors may be different for various sub - groups of Prostate Cancer, such as for aggressive and non - aggressive cancers, defined by stage, or survival. Premise, Usually Implicit, That Risk Factors For Initiation Of Relatively Innocuous, Well - Differentiate Prostate Cancers Should Be Same As Those That Cause Death From Prostate Cancer Has Little Theoretical Or Empirical Basis. Further, although many epidemiologic studies combine cancers at advanced stage at time of diagnosis and those with High Gleason Grade to characterize aggressive Prostate Cancer, this practice implicitly supposes that gradewhich reflects degree of differentiationcarries same meaning as advanced stage, but risk factors could influence progression of cancer independently of effect on tumor Grade. Thus, results across studies could vary depending on specific Prostate Cancer sub - type examine. In Health Professionals Follow - Up Study, we have report on various lifestyle and nutritional factors in relation to risk of Prostate Cancer. Most reports address single factors, and focus on cancer, or advanced disease at diagnosis as indicator of aggressive disease. In this report, we consider systematically 10 risk factors with cases from 1986 to 2002 in relation to various Prostate Cancer sub - types, specifically, total incident Prostate Cancer, fatal Prostate Cancer, advanced or non - advanced stage at presentation, High - Grade or low Grade Prostate Cancer, and some combinations of stage and grade. We examine in multivariable analysis 10 factors that we previously found to be predictors of Prostate Cancer incidence or advanced Prostate Cancer, and that have some in literature. These include cigarette smoking history, 6 race, family history of Prostate Cancer, physical activity, 8 body mass index, 9 height, 9 total energy consumption, 10 and intakes of calcium, 11 tomato sauce 12 and - linolenic acid. 13 14 Further, we consider how alternative definitions of clinically advanced Cancer influence results. In addition, we consider potential influence that PSA screening may have on identifying risk factors for total Prostate Cancer and advanced Prostate Cancer, because PSA screening advances time of diagnosis and alters spectrum of cancers that are diagnose. Finally, we consider risk factors differ for earlier - age onset and late - onset Prostate Cancer. Multivariable relative and 95 percentage confidence intervals in s for High category versus low or reference category for select variables from Cox models separately for total Prostate Cancer incidence and fatal Prostate Cancer in Health Professionals Follow - Up Study.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

What is advanced prostate cancer?

Prostate cancer is cancer that starts in prostate gland. Advanced prostate cancer occurs when it has spread, or metastasize, from prostate to other areas of body. Cancer spreads when cells break off from original tumor and invade nearby tissue. This is called localized metastasis. Cancer can spread directly into nearby tissues or through lymphatic system to distant parts of body. When this happen, it is called metastatic disease or prostate cancer with metastasis certain body part or organ system. New tumors can in any organ, but prostate cancer is most likely to spread to: adrenal gland, bones, liver, lungs. Stage 4 prostate cancer occurs when prostate cancer has already spread to distant organs or tissues at time of diagnosis. Most of time, doctors diagnose prostate cancer at earlier stage. It is generally slow - growing cancer, but it can spread or it can come back, or recur, after treatment.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

Sources

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions.

* Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions

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