Thalidomide

Summarized by Plex Health
Last Updated: 02 May 2022
thalidomide prevents the progression of peritoneal fibrosis in mice. "thalidomide prevents the progression of peritoneal fibrosis in mice.", by Arai H, Furusu A, Nishino T, Obata Y, Nakazawa Y, Nakazawa M, Hirose M, Abe K, Koji T, Kohno S. F2: Immunohistochemistry for CD31, PCNA, VEGF, and TUNEL. Note the presence of numerous vessels positively stained for CD31 (arrows) in the CG group (A), while few vessels are stained for CD31 (arrows) in the CG+thalidomide...

Thalidomide is used along with dexamethasone to deal with multiple myeloma. Thalidomide is additionally used to deal with and avoid modest to serious skin lesions caused by leprosy. Thalidomide may also be used for objectives not detailed in this medicine overview. Both women and men using this medicine ought to use reliable contraception to stop pregnancy during treatment, and for as much as 4 weeks after your last dosage. Thalidomide may cause embolism. Even women with fertility problems are needed to use contraception while taking thalidomide. Call your medical professional if you have had unprotected sex, even once, or if you think your female sexual partner may be pregnant. Thalidomide is only readily available as part of a special program called Thalomid REMS. Thalidomide is being studied in the therapy of other types of cancer. Definition from the NCI Drug Dictionary, Detailed scientific definition and other names for this drug. If they can help deal with or prevent conditions other than the ones they are authorized for, drugs are frequently examined to locate out. This patient information sheet uses only to accepted uses of the medicine. Discover Clinical Trials for Thalidomide, Check for tests from NCI's list of cancer clinical trials now approving patients. Thalidomide is a beige to white, odorless, crystalline powder that is soluble at 25 C in dimethyl sulfoxide and moderately soluble in water and ethanol. THALOMID is readily available in 50 mg, 100 mg, 150 mg and 200 mg capsules for oral administration. The 100 mg capsule covering has black iron oxide, yellow iron oxide, titanium dioxide, jelly, and black ink.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
5426C13H10N2O4258.23C1CC(=O)NC(=O)C1N2C(=O)C3=CC=CC=C3C2=OC1CC(=O)NC(=O)C1N2C(=O)C3=CC=CC=C3C2=OInChI=1S/C13H10N2O4/c16-10-6-5-9(11(17)14-10)15-12(18)7-3-1-2-4-8(7)13(15)19/h1-4,9H,5-6H2,(H,14,16,17)UEJJHQNACJXSKW-UHFFFAOYSA-N2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione0.3258.06405680258.0640568083.644901411901010001
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