Thyrogen

Summarized by Plex Health
Last Updated: 04 May 2022

Thyrogen is a manufactured type of a protein comparable to thyroid-stimulating hormone, which is normally created and launched into the bloodstream by the pituitary gland. TSH controls production of the thyroid hormones, thyroxine and triiodothyronine, by the thyroid gland by binding to receptors located on cells in the thyroid gland This medicine maintains your TSH degrees steady while you undergo thyroid tests or therapies that can lower TSH and cause symptoms of low thyroid. Thyrogen is used together with contaminated iodine ablation in people with thyroid cancer. Thyrogen is additionally used during medical testing to look for particular types of thyroid cancer that has returned after treatment. This medication may not assist your doctor locate all signs of cancer, and there is still a chance that a few of your cancer might be missed. Thyrogen will not treat cancer that has infected other parts of the body. Thyrogen may additionally be used for functions not detailed in this medication guide. You should not use Thyrogen if you are sensitive to it. Thyrogen is usually offered in 2 separate injections 24 hours apart. You may additionally be provided contaminated iodine to take 24 hours after your last Thyrogen injection. You may be provided steroid medication to help keep tumors from growing larger while you are obtaining Thyrogen. Your physician may want you to obtain Thyrogen in a health center or facility setup to promptly deal with any significant side effects that occur. You may not observe any change in your symptoms, yet your blood work will help your physician figure out whether treatment has worked.

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Research Papers' Summaries

PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
50070190C41H49ClN6O5741.3CC1=C(C=C(C=C1)C(=O)NC2=CC=CC=C2C)NC(=O)C(C)N3CCC(CC3)C(=O)N4CCCC4C(=O)NC5=C(C=C(C=C5)Cl)C(=O)NC6CCCC6CC1=C(C=C(C=C1)C(=O)NC2=CC=CC=C2C)NC(=O)C(C)N3CCC(CC3)C(=O)N4CCCC4C(=O)NC5=C(C=C(C=C5)Cl)C(=O)NC6CCCC6InChI=1S/C41H49ClN6O5/c1-25-9-4-7-12-33(25)44-38(50)29-15-14-26(2)35(23-29)46-37(49)27(3)47-21-18-28(19-22-47)41(53)48-20-8-13-36(48)40(52)45-34-17-16-30(42)24-32(34)39(51)43-31-10-5-6-11-31/h4,7,9,12,14-17,23-24,27-28,31,36H,5-6,8,10-11,13,18-22H2,1-3H3,(H,43,51)(H,44,50)(H,45,52)(H,46,49)WHIQRIMZPBHQHC-UHFFFAOYSA-NN-[4-chloro-2-(cyclopentylcarbamoyl)phenyl]-1-[1-[1-[2-methyl-5-[(2-methylphenyl)carbamoyl]anilino]-1-oxopropan-2-yl]piperidine-4-carbonyl]pyrrolidine-2-carboxamide6.2740.3452964740.34529641401300046105302020001
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