Torsemide

Summarized by Plex Health
Last Updated: 02 May 2022
effect of aliskiren, telmisartan and torsemide on cardiac dysfunction in l-nitro arginine methyl ester (l-name) induced hypertension in rats. "effect of aliskiren, telmisartan and torsemide on cardiac dysfunction in l-nitro arginine methyl ester (l-name) induced hypertension in rats.", by Sadek SA, Rashed LA, Bassam AM, Said ES. f0005: Graph of collagen I & III expression in all groups. ∗Significant at P < 0.05 compared l-NAME group to normal, aliskiren, telmisartan and torsemide control groups. ■Significant at P < 0.05 compared aliskiren, telmisartan...

Torsemide is a loop diuretic that is used to deal with fluid retention in people with heart failure, liver disease, or kidney disease. Torsemide is also used to treat high blood pressure. Torsemide might be used for functions not provided in this drug overview. It is not known whether torsemide will harm unborn baby. A medical care provider might educate you just how to effectively use the medication on your own. You may take torsemide with or without food. If you have high blood pressure, keep taking torsemide oral even if you feel well. High blood pressure often has no symptoms. You might need to use blood pressure medication for the remainder of your life. Its chemical name is 1-isopropyl-3 [sulfonyl] urea and its structural formula is: Its empirical formula is C16H20N4O3S, its pKa is 7. 1, and its molecular weight is 348. 43. Torsemide is a white to beige crystalline powder. The tablets for oral administration also consist of lactose NF, crospovidone NF, povidone USP, microcrystalline cellulose NF, and magnesium stearate NF. Torsemide ampuls for intravenous injection consist of a sterile solution of torsemide, polyethylene glycol-400 NF, tromethamine USP, and salt hydroxide NF in water for injection USP. This medication works by acting on the kidneys to increase the circulation of urine. High blood pressure includes in the work of the heart and arteries. If it continues for a very long time, the heart and arteries may not function appropriately. High blood pressure may also increase the risk of heart attacks. These troubles may be less likely to occur if blood pressure is regulated. This medicine is available only with your medical professional's prescription.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
41781C16H20N4O3S348.4CC1=CC(=CC=C1)NC2=C(C=NC=C2)S(=O)(=O)NC(=O)NC(C)CCC1=CC(=CC=C1)NC2=C(C=NC=C2)S(=O)(=O)NC(=O)NC(C)CInChI=1S/C16H20N4O3S/c1-11(2)18-16(21)20-24(22,23)15-10-17-8-7-14(15)19-13-6-4-5-12(3)9-13/h4-11H,1-3H3,(H,17,19)(H2,18,20,21)NGBFQHCMQULJNZ-UHFFFAOYSA-N1-[4-(3-methylanilino)pyridin-3-yl]sulfonyl-3-propan-2-ylurea2.7348.12561169348.1256116910951803552400000001
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