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Tramadol

Summarized by Plex Health
Last Updated: 02 May 2022
biochemical and neurotransmitters changes associated with tramadol in streptozotocin-induced diabetes in rats. "biochemical and neurotransmitters changes associated with tramadol in streptozotocin-induced diabetes in rats.", by Ezzeldin E, Souror WA, El-Nahhas T, Soudi AN, Shahat AA. fig8: (a) Kidney of normal rat treated with 100 mg/kg tramadol. Degeneration and cystic dilatation in the tubules at the corticomedullary junction, HE ×64. (b) Kidney of diabetic rat treated with 100 mg/kg tramadol. Swelling...

Tramadol is a pain medication comparable to an opioid and is categorized as a synthetic opioid. Tramadol is used to deal with moderate to serious pain in adults. The extended-release type of tramadol is for continuous therapy of pain. Seizure risk is additionally higher in those with a seizure disorder or those taking particular antidepressants or opioid medicines. Taking tramadol while pregnant may cause dangerous withdrawal symptoms in the newborn. Tramadol needs to not be provided to a child more youthful than 12 years of ages. Never share tramadol with another person, particularly somebody with a history of drug dependency. If you have long term pain, your medical professional might also prescribe it if weak painkillers no longer work. Tramadol does not stop the pain totally, however you will not be able to feel it as much. Tramadol is readily available only on prescription. It's possible to become addicted to tramadol, however your physician will describe exactly how to lower those risks. If you require to take tramadol for more than a few weeks, your treatment strategy might consist of details of just how and when to quit taking this medication. It's best not to drink alcohol with tramadol as you're most likely to get side effects, like feeling drowsy. Tramadol comes from the group of medicines called opioid anesthetics. People that have proceeding pain should not allow the concern of reliance keep them from making use of narcotics to alleviate their pain. When narcotics are used for this function, psychological dependancy is not likely to occur. If treatment is stopped all of a sudden, physical dependancy may lead to withdrawal side effects. Nonetheless, severe withdrawal side effects can usually be protected against by gradually minimizing the dose over a time period before treatment is quit totally. This medicine is offered only under a limited circulation program called the Opioid Analgesic REMS program.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
33741C16H25NO2263.37CN(C)CC1CCCCC1(C2=CC(=CC=C2)OC)OCN(C)C[[email protected]]1CCCC[[email protected]@]1(C2=CC(=CC=C2)OC)OInChI=1S/C16H25NO2/c1-17(2)12-14-7-4-5-10-16(14,18)13-8-6-9-15(11-13)19-3/h6,8-9,11,14,18H,4-5,7,10,12H2,1-3H3/t14-,16+/m1/s1TVYLLZQTGLZFBW-ZBFHGGJFSA-N(1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexan-1-ol2.6263.188529040263.18852904032.728201341902200001
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