Valproic Acid

Summarized by Plex Health
Last Updated: 02 May 2022
inhibition of leukemic cells by valproic acid, an hdac inhibitor, in xenograft tumors. "inhibition of leukemic cells by valproic acid, an hdac inhibitor, in xenograft tumors.", by Zhang Z, Hao C, Wang L, Liu P, Zhao L, Zhu C, Tian X. f4-ott-6-733: Valproic acid downregulates transcription of cyclin D1, cyclin E1, CDK4, and CDK6, and upregulates transcription and protein expression of p21. Comparison between control group and valproic acid after two weeks of treatment. (A) Expression...

Valproic acid is used to treat numerous types of seizure disorders. Valproic acid is often used along with other seizure medicines. Valproic acid is additionally used to deal with manic episodes connected to bipolar disorder, and to stop migraine headache headaches. Valproic acid might additionally be used for purposes not noted in this medication overview. Valproic acid can cause liver failure that might be deadly, particularly in children under age 2 and in people with liver troubles brought on by specific congenital diseases. Utilizing valproic acid during maternity may increase the risk of serious abnormality that can develop early in pregnancy, even prior to you know you are pregnant. If you are pregnant or you can end up being pregnant, do not use valproic acid to stop migraine headache headaches. You'll usually take valproic acid 2 or 3 times a day. Sodium valproate and semisodium valproate resemble valproic acid and operate in the same way. For epilepsy and bipolar affective disorder, your medical professional will only prescribe valproic acid for you if there are no other appropriate treatments. Valproic acid is not ideal for women or girls who can conceive. Girls and women who need to take valproic acid has to be on Prevent, the valproate maternity avoidance programme. To make certain valproic acid is risk-free for you, inform your physician if you: have ever before had an allergy to valproic acid or any other medication; have liver issues; have a rare metabolic or hereditary condition such as porphyria, urea cycle disorder or mitochondrial disorder. The spray capsule may be ingested whole or sprinkled on soft food, such as applesauce or dessert. The postponed launch tablets and the soft gelatin pill need to be ingested entire. Do not mix the syrup with soda water drinks. If stomach upset occurs, take valproic acid with food. Do not quit taking this medicine up until your physician informs you to do so. When you first start taking it, the medical professional will slowly increase your dosage of valproic acid. This medication may cause you to feel dizzy and sluggish. It is very vital that you take valproic acid specifically as routed. Valproic acid may affect the way other medicines work. Numerous medicines can increase the side effects of valproic acid or increase the blood level of valproic acid. The staff will draw blood samples consistently to look for changes in liver function.

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PubChem - CovalentUnitCount

(Table source)
3121C8H16O2144.21CCCC(CCC)C(=O)OCCCC(CCC)C(=O)OInChI=1S/C8H16O2/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H,9,10)NIJJYAXOARWZEE-UHFFFAOYSA-N2-propylpentanoic acid2.8144.115029749144.11502974937.39301251000000001
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