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Vigabatrin

Summarized by Plex Health
Last Updated: 02 May 2022
clinical profile of vigabatrin as monotherapy for treatment of infantile spasms. "clinical profile of vigabatrin as monotherapy for treatment of infantile spasms.", by Lerner JT, Salamon N, Sankar R. f3-ndt-6-731: A1 and A2) show axial T2 weighted images of a normal baby aged five months. B1 and B2) show a five-month-old patient who had received vigabatrin for eight weeks. The magnetic resonance image was...

Vigabatrin, USP is an oral antiepileptic medication and is available as a white to beige granular powder for oral option in packets of 500 mg. Vigabatrin is an anticonvulsant or antiepileptic substance abuse to treat epilepsy and infantile convulsions. The n-octanol/water dividers coefficient of vigabatrin is about 0. 011 log P=-1. 96 at physiologic pH. Vigabatrin, USP thaws with decay in a 3-degree range within the temperature interval of 171 C to 176 C. The dissociation constants of vigabatrin are 4 and 9. 7 at area temperature level. Vigabatrin for oral service USP, is readily available as white to beige granular powder for oral administration. Vigabatrin helps to increase the amount of GABA in your central nerve system by obstructing the action of an enzyme called GABA-T, which assists to damage down GABA when it is not needed. If these side effects take place in babies who take vigabatrin, it is not understood. Vigabatrin might make specific types of seizures worse if you or your child has intricate partial seizures. You should inform your infant's health care provider right away if your infant's seizures worsen. It is used in patients that have already been treated with other medications that did not work well. Vigabatrin is an anticonvulsant. It increases the amount of the chemical called gamma amino butyric acid in the brain. Some seizures are triggered by low levels of GABA. It reduces the chance of a seizure when vigabatrin increases GABA. This medicine is offered only with your medical professional's prescription.

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PubChem - CovalentUnitCount

(Table source)
CIDMolecularFormulaMolecularWeightCanonicalSMILESIsomericSMILESInChIInChIKeyIUPACNameXLogPExactMassMonoisotopicMassTPSAComplexityChargeHBondDonorCountHBondAcceptorCountRotatableBondCountHeavyAtomCountIsotopeAtomCountAtomStereoCountDefinedAtomStereoCountUndefinedAtomStereoCountBondStereoCountDefinedBondStereoCountUndefinedBondStereoCountCovalentUnitCount
5665C6H11NO2129.16C=CC(CCC(=O)O)NC=CC(CCC(=O)O)NInChI=1S/C6H11NO2/c1-2-5(7)3-4-6(8)9/h2,5H,1,3-4,7H2,(H,8,9)PJDFLNIOAUIZSL-UHFFFAOYSA-N4-aminohex-5-enoic acid-2.2129.078978594129.07897859463.31120234901010001
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