Summarized by Plex Health
Last Updated: 02 May 2022
genetic variation in plant cyp51s confers resistance against voriconazole, a novel inhibitor of brassinosteroid-dependent sterol biosynthesis. "genetic variation in plant cyp51s confers resistance against voriconazole, a novel inhibitor of brassinosteroid-dependent sterol biosynthesis.", by Rozhon W, Husar S, Kalaivanan F, Khan M, Idlhammer M, Shumilina D, Lange T, Hoffmann T, Schwab W, Fujioka S, Poppenberger B. pone-0053650-g006: Voriconazole inhibits growth of monocotyledonous and dicotyledonous crop plants.Phenotypes of plants grown on control media (left) or media containing 1 µM voriconazole (right). The days after germination are indicated in brackets. The white scale...

Voriconazole USP, an azole antifungal agent is readily available as film-coated tablets for oral administration. The structural formula is: Voriconazole is assigned chemically as-5 fluoro- methyl- 4pyrimidineethanol with an empirical formula of C16H14F3N5O and a molecular weight of 349. 31 g/mole. Voriconazole drug substance is a white or virtually white powder. Voriconazole tablets include 50 mg or 200 mg of voriconazole. The non-active active ingredients consist of croscarmellose salt, lactose monohydrate, magnesium stearate, povidone, pregelatinized starch, and a covering including hypromellose, lactose monohydrate, titanium dioxide, and triacetin. A genetic test can be done to see if your CYP2C19 breaks down medications slower or faster than normal. If your body breaks down the medicine slower or faster than normal, you may require to get a various dose of voriconazole or a various medicine. Food may keep voriconazole from soaking up well. Take voriconazole one hour before a dish or one hr after a meal. Discard the bottle after 14 days or when the expiration day on the tag informs you to do so. It may be used to deal with patients with significant fungal or yeast infections who can not endure or do not reply to other types of treatment. This medicine is readily available only with your physician's prescription.

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PubChem - CovalentUnitCount

(Table source)
71616C16H14F3N5O349.31CC(C1=NC=NC=C1F)C(CN2C=NC=N2)(C3=C(C=C(C=C3)F)F)OC[[email protected]@H](C1=NC=NC=C1F)[[email protected]](CN2C=NC=N2)(C3=C(C=C(C=C3)F)F)OInChI=1S/C16H14F3N5O/c1-10(15-14(19)5-20-7-22-15)16(25,6-24-9-21-8-23-24)12-3-2-11(17)4-13(12)18/h2-5,7-10,25H,6H2,1H3/t10-,16+/m0/s1BCEHBSKCWLPMDN-MGPLVRAMSA-N(2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol1.5349.11504457349.1150445776.744801852502200001
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