X-Linked Sideroblastic Anemia

Summarized by Plex Health
Last Updated: 03 May 2022

X-linked sideroblastic anemia is an acquired disorder that protects against developing red blood cells from making adequate hemoglobin. People with X-linked sideroblastic anemia have mature red blood cells that are smaller sized than normal and appear pale due to the lack of hemoglobin. This disorder results in an abnormal accumulation of iron in red cell. The signs and symptoms of X-linked sideroblastic anemia result from a combination of decreased hemoglobin and an overload of iron. X-linked sideroblastic anemia is triggered by mutation in the ALAS2 genetics. X-linked sideroblastic anemia is inherited in an X-linked recessive pattern.

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