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The novel coronavirus outbreak, coronavirus disease 2019, which was declared pandemic by the World Health Organization on March 11 2020, has infected over 4 million people and caused nearly 300 000 fatalities in over 188 countries. Intensive effort is ongoing worldwide to establish effective treatments and develop vaccines for disease. Novel coronavirus, named as severe acute Respiratory Syndrome coronavirus 2, belongs to the family of pathogen that is responsible for respiratory illnesses linked to the 2002-2003 outbreak. The Envelop virus contains a positive-sense single-strand RNA genome and a nucleocapsid of helical symmetry of 120 nm. There exist several plausible pathways for viruses to be transmitted from person to person. Human atomization of virus-bearing particles occurs from coughing / sneezing and even from normal breathing / talking by an infected person. These mechanisms of viral shedding produce large droplets and small aerosols, which are conventionally delineate at size of 5 m to characterize their distinct dispersion efficiencies and residence times in air as well as deposition patterns along the human respiratory tract. Virus transmission occurs via direct or indirect contact and airborne routes. Large droplets readily settle out of the air to cause person / object contamination; in contrast, aerosols are efficiently disperse in the air. While transmission via direct or indirect contact occurs in short range, airborne transmission via aerosols can occur over extended distances and time. Inhale virus-bearing aerosols deposit directly along the human respiratory tract. Previous experimental and observational studies on interhuman transmission have indicated significant role of aerosols in transmission of many respiratory viruses, including influenza virus, SARS-CoV-1, and Middle East Respiratory Syndrome coronavirus. For example, airborne coronavirus MERS-CoV exhibits strong capability of surviving, with about 64% of microorganisms remaining infectious 60 min after atomization at 25 C and 79% relative humidity. On the other hand, rapid virus decay occur, with only 5% survival over 60-min procedure at 38 C and 24% RH, indicative of inactivation. Recent experimental studies have examined the stability of SARS-CoV-2, showing that the virus remains infectious in aerosols for hours and on surfaces up to days. Several parameters likely influence microorganism survival and delivery in air, including temperature, humidity, microbial resistance to external physical and biological stresses, and solar ultraviolet radiation. Transmission and infectivity of airborne viruses are also dependent on the size and number concentration of inhaled aerosols, which regulate amount and pattern for respiratory deposition. With typical nasal breathing, inhalation of airborne viruses leads to direct and continuous deposition into the human respiratory tract. In particular, fine aerosols penetrate deeply into the respiratory tract and even reach other vital organs. In addition, viral shedding is dependent on stages of infection and varies between symptomatic and asymptomatic carriers. Recent findings show that the highest viral load in the upper respiratory tract occurs at symptom onset, suggesting peak of infectiousness on or before symptom onset and substantial asymptomatic transmission for SARS-CoV-2.
Route 11 first appeared at the end of Aura Storm. As shown in Calling from Beyond Aura!, Locate along is Forest Mountain with some rocky areas. Cave full of Noibat leads to Pomace Mountain, which is located along the route. After Pomace Mountan is Forest area, visit in Forest Champion!. The forest also has cave and waterfall. Fighting Pokemon are common in this area. Ash also caught his Hawlucha in this Forest. After Forest is Kalos Canyon as shown in Battles in Sky!. Ash and his friends visit the Reflection Cave in the Cave of Mirrors!. Pokemon Center is located somewhere after the Cave as mentioned in the episode. After the Cave is Forest path, which was visited in Forging Forest Friendships!. After Forest is the location of Kalos's Pokemon Summer Camp, as shown in Summer of Discovery!. It is located along the coast of Kalos.
|Viola||Santalune City||Bug||Vivillon||Bug Badge|
|Grant||Cyllage City||Rock||( ) Tyrunt||Cliff Badge|
|Korrina||Shalour City||Fighting||Lucario Hawlucha||Rumble Badge|
|Ramos||Coumarine City||Grass||Gogoat||Plant Badge|
|Clemont||Lumiose City||Electric||Heliolisk||Voltage Badge|
|Valerie||Laverre City||Fairy||Sylveon||Fairy Badge|
|Olympia||Anistar City||Psychic||Meowstic||Psychic Badge|
|Wulfric||Snowbelle City||Ice||Avalugg||Iceberg Badge|
When implementing the Quarters scheme, Four Read is Day 1 install coverage and DCs most likely first down call. The Cover 4 scheme allows safeties to be ultra aggressive to run, yet hold two-high shell and keep defense balance versus multiple formations. Defensive coaches lean on the Cover 4 scheme because it allows the defense to essentially create a nine-Man box versus spread sets. For most spread teams, OC do not account for two safeties. This is where teams running quarters scheme gain advantage. DCs usually rely on a true Cover 2 scheme to gain the hard edge over CBs against run. This leaves the defense vulnerable on the edge of the box, passing lanes in the middle of the field, and puts Mike in a run / pass conflict. As modern football has turned to spread, more DCs are turning to variations of match quarters to answer their run and pass distribution problems. In previous article, I touched on the basics of passing distributions of Four and Two Read. In today's article, I will go in-depth on the intricacies of each and popular route combinations. 1 There have been many arguments over who should take the sail route deep out in 2-Read Cloud. I teach my CBs in Cloud to drive through 1 WR when breaking on any out route by 2, basically knocking him off his path and forcing him into Saf. Even though 2 WRs go deeper than LB depth which some consider Vertical, CB has to keep his eyes on 2. In Cloud coverage, CB is technically an intermediate Zone player. So, If team run Flood you have to play it just like fade / Sail. CB will come off 1 and drive on Sail. This is why Saf needs to fast bail in Cloud. He needs enough depth to drive on 1 vertically even if 2 runs deep out. Remember, anything underneath is not Safs responsibility, so he should climb to the next Vertical and only drive on ball thrown. Conclusion, CB will drive on Sail with help underneath from OLB. Saf will fast bail out and climb. As 2 breaks out on Sail, Saf will climb to meet 1 collision is keyed by CB to slow vert of 1. Sail is a long throw for HS QBs, CB should have time to drive on it. 2 RB in any 22 set is Mikes responsibility 3 WR and he will push with RB until the route either breaks into new 3 or continue to push if 1 / 2 go Vertical. In 31, RB is 2 weak, and OLB will push. I teach my OLBs in Match Quarters to carry their man until they are crossed by another or push off their man. So, in Flood ex.
Electrochemical methods have been employed to advantage for synthesis of many solid materials. Typical materials prepared in this manner are metal borides, carbides, suicides, oxides and sulfides. Vanadate spinels of formula MV 2 O 4 as well as tungsten bronze 5 WO 3 have been prepared by electrochemical Route. Electrochemical oxidation has been employed to prepare oxygenexcess La 2 CuO 4 and other related materials. Thin films of BaTiO 3 and lead zirconate Titanate have been prepared by cathodic reduction. Intercalation of alkali metals in host solids is readily accomplished electrochemically. The Synthetic Route for target molecule CAN be represented as a tree-like structure in which molecule nodes and chemical reactions appear alternately, as shown in Fig. 2. In order to make Route feasible, end molecule nodes molecules in blue circles in Fig. 2 must consist of starting materials, and each synthesis STEP should be reasonable. The Chemical reaction network of target molecules is typically large and CAN efficiently express possible synthetic routes to target represented by molecule and reaction nodes. In this study, we represent synthetic routes and chemical reaction networks as and / or trees, as shown in Fig. 2, to efficiently construct chemical reaction networks and precisely perform enumeration. Synthetic Route in Fig. 2 is represented as the black Route in Fig. 2 by expressing molecule and reaction nodes as or and and nodes, respectively. Gray Route in Fig. 2 shows another route to synthesize the same reactant. In and / or tree, molecule is represented as or node because either black or gray routes are available to synthesize the same reactant, as shown in Fig. 2. On other hand, reaction is represented as and node because all reactants E. G, B and C or nodes in Fig. 2 of reaction and node in Fig. 2 are required to synthesize product. Merging molecules and reaction nodes that appear in different synthetic routes in this manner Fig. 2 enables efficient representation of large number of routes as chemical reaction network Fig. 2. CompRet efficiently constructs a chemical reaction network for giving target molecule based on DFPN, search method based on and / or tree using proof and disproof numbers for each node. To design synthetic Route, reaction templates are applied to the target to transform it into reactants. For retrosynthetic computation, Reactor version 20. 11. 0, which CAN consider stereochemistry in reaction templates, was used Relevance of transformed reactants was checked by computing products of template and reactants. By recursively performing this transformation according to the DFPN algorithm, all possible synthetic routes for target molecule CAN be obtained upon reaching preset maximum depth md. Algorithms can design longer synthetic routes with larger md value. Furthermore, CompRet repeatedly searches for new Route and merges it into a chemical reaction network.
Since the 1960s, several researchers have proposed computer-assisted chemical synthetic route designs. Various computer-assisted synthesis planning programs have been developed to assist synthetic organic chemists in their work. While expert systems and knowledge-base programs were the primary focus of CASP during early stages, recent breakthroughs in the field of deep learning and widespread availability of reaction datasets have accelerated its development. In particular, data-driven approaches have received attention across research fields. These approaches for multi-step synthesis planning have shown outstanding performance at every stage, and more recently, they have provided realistic and preferable synthetic routes. The Pioneers of CASP, Corey and Wipke, state the following requirements relate to the above strategy in their paper: program needs to provide as many useful routes as possible, chemists can decide depth of search or analysis of synthetic route, and give routes are evaluated by chemists. As discussed above, several CASP approaches have been develop; however, majority of them have aim to directly obtaining optimal chemical synthetic route rather than attempting to provide multiple route candidates. According to Corey, examining as many useful chemical synthetic routes as possible is an essential part of retrosynthetic analysis. It is well known that evaluation criteria used for presented synthetic routes depend on chemists ' situation, objectives, and / or needs, such as early-stage derivatization of hits, optimization of lead compounds, or large-scale synthesis of drug candidates. Thus, desirable framework should provide as many useful routes as possible under specific conditions and choose multiple reliable routes based on given situations. As framework for providing multiple reliable routes, Kowalik et al. Have developed a promising approach using Network of Organic Chemistry and enumeration algorithm of possible synthetic routes. NOC consists of all possible molecules and reactions that represent links from reactants to products. Reactions are practically represented as templates that include conditional / contextual rules of chemistry. Additionally, they implement a recommendation system of multiple synthetic routes for target molecule as follow. Firstly, they extract a network of molecules and reactions relate to target from NOC. Secondly, they enumerate all possible synthetic routes from the chemical reaction Network, and then, select promising candidate routes. Although they show vast number of synthetic routes for some molecules and present realistic solutions, their approach has two potential issues: NOC is very large, and thus, uneconomical for obtaining optimal routes for specific target molecule, and enumeration algorithms do not always provide all possible routes. Hence, efficient algorithm for constructing chemical reaction Network is required for practical application. Further, exact enumeration algorithm without loss or duplication is needed for practical usage and finding reliable alternative routes. In this study, we propose a CASP framework called CompRet, which enumerates possible synthetic routes using a novel enumeration algorithm with theoretical guarantee, and then selects useful routes based on several score functions.
In this Xs and Os breakdown breakdown we take a look at some of the more common passing routes that you will find throughout football video games such AS Madden and NCAA. Every passing concept and route combination has some sort of passing route. Some passing routes work better than others Vs certain types of Pass coverages. Halfbacks and fullbacks run this Route of backfield. Back Start off by going towards outside, and then angle back towards the middle of the field. Angle Route is effective against man coverage if the back has more speed than the defender covering him. It also works against Zone coverage by having another receiver run Route over top such AS slant or in Route. The receiver takes one step back and then runs Horizontally with his eyes on the QB waiting for the throw, He then catches it and runs up field. Effective Route Vs blitz and soft Zone coverage. If a blitz is call, and the defender covering him man coverage is playing off, throw quickly to the receiver. All it takes is for a receiver to break one tackle for a big play. The receiver ran straight downfield and then towards the corner of the end zone. It is a good Pass Route to beat Cover 2 if cornerbacks play in short or flat Zone area. Against man coverage, it can be effective, but you need to take control of the receiver. The receiver runs up field about 8-10 yards and then curls back towards the quarterback. Effective Pass Route against man and Zone coverage. If throw right, receiver can take control of to make high leaping catch. The receiver runs 12-15 yards and round his Route across the field. Very effective Pass Route against man coverage, especially if the receiver has more speed than the defender covering him. Good Pass Route to beat man or soft Zone coverage. The receiver runs straight downfield for 15-20 yards and then hooks back in or out towards the quarterback. The receiver runs downfield for 10-15 yards and then cuts towards the middle of field. This is a good Route to beat underneath coverage. Good Pass Route to beat soft Zone coverage such AS Cover 4. The receiver runs 10-15 yards and then cuts in at a 90-degree angle towards the sideline. These types of route have tight end, or runningback delays before going out on their Pass Route. The reason they delay is because they look like they are Pass blocking. In some cases, such AS when blitz is called on their side of the ball, they wont even go out. Routes such seam, flat, or curl are types of delay routes you will find in the game. Delay routes are indicated by them being blue. Any tight end or runningback cannot be send into motion when running delay Route.
|1||Install driver partitions, which will prevent patrons from having direct contact with the driver|
|2||Require drivers to wear facial coverings, effective June 15.|
|3||Limit seating on SolanoExpress to no more than 20 riders so that patrons are adhering to social distancing.|
|4||Promote cashless payment.|
|5||Enhanced cleaning protocols on buses and transit facilities.|
The first stop of the Y bus route is Vallejo Transit Center and the last stop is Walnut Creek Bart. Y is operational everyday. Additional information: Y has 11 stops and the total trip duration for this route is approximately 48 minutes. On go? See why over 865 million users trust Moovit as the best public transit app. Moovit gives you SolTrans suggest routes, real-time bus tracker, live directions, line route maps in San Francisco-San Jose, CA, and helps to find the closest Y bus stops near you. No internet available? Download offline PDF map and bus schedule for Y bus to take on your trip.
|4||A Quiet Ride Campaign|
|5||Vehicle and Facility Conditions-Ventilation|
|7||Personal Protective Equipment (PPE)|
|8||Infected Employees/contact tracing|
The UNESCO Office in San Jose has developed Collection del Olvido la memoria, educational materials on the influence of Afro-descend in Central America. Produce in collaboration with the University of Costa Rica and the National Museum of the country, this Collection includes a five volume series of Teaching materials that are part of an initiative of Central America countries to eliminate ignorance about the influence of populations of African descent in the region. Fund by UNESCO, this series of publications is part of the Slave Route Project and accompanies its new orientations with regard to geographical expansion to regions insufficiently covered on this topic and introduction of new themes. Besides dissemination of these materials, UNESCO is working actively towards their inclusion into curricula of Central America countries and organizing workshops to: validate the content of brochures prepared by UNESCO on African presence in Central America Provide teachers with suggestions and recommendations for working with students, promoting learning about African heritage in each country Obtain recommendations to implement study of history, presence and Contribution of Africans in Central America in educational programs of Ministries of Education respectively as of 2018, building Our Nation: Contribution of Afro-Caribbean Migration in Costa Rica is available online. This is a mini-series of documentaries that can be used as educational tool, produced by the Chair of African and Caribbean Studies and Vice-Rectory of Teaching of University of Costa Rica, with support of UNESCO. Four documentaries provide a first-hand account, through testimonies, of the experience of migrants from Caribbean islands in the process of integrating their descendants into country.
The Silk Route was a historic trade route that dates from the second Century BC until 14 Century AD. It stretches from Asia to the Mediterranean, traversing China, India, Persia, Arabia, Greece, and Italy. It was dubbed the Silk Route because of heavy Silk trading that took place during that period. This valuable fabric originated in China, which initially had a monopoly on Silk production until secrets of its creation spread. In addition to Silk, Route facilitates trade in other fabrics, spices, grains, fruits and vegetables, animal hides, wood and metal work, precious stones, and other items of value. In 2013, China announced plans to revive the Silk Route, connecting it with more than 60 countries in Asia, Europe, Africa, and the Middle East.
Coronavirus Disease 2019 pandemic has raised long-standing debate about the extent to which common respiratory viruses, including severe acute respiratory syndrome coronavirus 2, are transmitted via respiratory droplets and aerosols. Droplets are classically described as larger entities that rapidly drop to the ground by force of gravity, typically within 3 to 6 feet of the source person. Aerosols are smaller particles that rapidly evaporate in air, leaving behind droplet nuclei that are small enough and light enough to remain suspended in the air for hours. Determining whether droplets or aerosols predominate in transmission of SARS-CoV-2 has critical implications. If SARS-CoV-2 is primarily spread by respiratory droplets, wearing a medical mask, face shield, or keeping 6 feet apart from other individuals should be adequate to prevent transmission. If, however, SARS-CoV-2 is carried by aerosols that can remain suspended in air for prolonged periods, medical masks would be inadequate, face shields would provide only partial protection, and 6 feet of separation would not provide protection from aerosols that remain suspended in air or are carried by currents. Experimental data support the possibility that SARS-CoV-2 may be transmitted by aerosols even in the absence of aerosol-generating procedures. Investigators have demonstrated that speaking and coughing produce mixture of both droplets and aerosols in a range of sizes, that these secretions can travel together for up to 27 feet, that it is feasible for SARS-CoV-2 to remain suspended in the air and viable for hours, that SARS-CoV-2 RNA can be recovered from air samples in hospitals, and that poor ventilation prolongs amount of time that aerosols remain airborne. 1 many of these same characteristics have previously been demonstrated for influenza and other common respiratory viruses. These data provide a useful theoretical framework for possible aerosol-base transmission for SARS-CoV-2, but what is less clear is the extent to which these characteristics lead to infections. Demonstrating that speaking and coughing can generate aerosols or that it is possible to recover viral RNA from air does not prove aerosol-base transmission; infection depends as well on route of exposure, size of inoculum, duration of exposure, and host defenses. Notwithstanding experimental data suggesting the possibility of aerosol-base transmission, data on infection rates and transmissions in populations during normal daily life are difficult to reconcile with long-range aerosol-base transmission. First, reproduction number for COVID-19 before measures were taken to mitigate its spread was estimated to be about 2. 5, meaning that each person with COVID-19 infected an average of 2 to 3 other people. This reproduction number is similar to influenza and quite different from that of viruses that are well known to spread via aerosols, such as measles, which has a reproduction number closer to 18. Considering that most people with COVID-19 are contagious for about 1 week, reproduction number of 2 to 3 is quite small given the large number of interactions, crowds, and personal contacts that most people have under normal circumstances within a 7-day period.
Two terms, import and export, explain how routes move between routing protocols and routing table. When the Routing Engine places routes of Routing Protocol into the routing table, it IS importing routes into the routing table. When the Routing Engine uses active routes from the Routing table to send Protocol advertisement, it IS exporting routes from the Routing table. Note the process of moving routes between Routing Protocol and Routing table IS described from the point of view of the Routing table. That IS, routes are imported into the Routing table from Routing Protocol and they are exported from the Routing table to Routing Protocol. Remember this distinction when working with Routing policies. AS shown in Figure 1, you use import routing policies to control which routes are placed on the routing table, and export routing policies to control which routes are advertised from the routing table to neighbors. In general, routing protocols place all their routes on the routing table and advertise a limited set of routes from the routing table. General rules for handling Routing Information between routing protocols and routing tables are known as the AS Routing policy framework. The routing policy framework IS compose of default rules for each Routing Protocol that determine which route protocol places on the routing table and advertising from the routing table. The default rules for each Routing Protocol are known AS default routing policies. You can create routing policies to preempt default policies, which are always present. Routing policy allows you to modify the routing policy framework to suit your needs. You can create and implement your own routing policies to do following: control which rout routing protocol places on the routing table. Control which active routes Routing Protocol advertises from the routing table. Active route IS a route that IS chosen from all routes on route table to reach destination. Manipulate route characteristics AS Routing Protocol places routes on the routing table or advertises routes from the routing table. You can manipulate route characteristics to control which route IS select AS active route to reach your destination. Active route IS place in forwarding table and IS Use to forward traffic toward routes destination. In general, active route IS also advertise to routers neighbors.
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